Ruthenium coordination compounds of biological and biomedical significance. DNA binding agents

V Brabec, J Kasparkova - Coordination chemistry reviews, 2018 - Elsevier
Ruthenium complexes exhibit a broad variety of biological and biomedical activities
including anticancer efficiency. The reason is that the octahedral bonding of both Ru (II) and …

Construction of homo and heteronuclear Ru (II), Ir (III) and Re (I) complexes for target specific cancer therapy

S Pete, N Roy, B Kar, P Paira - Coordination Chemistry Reviews, 2022 - Elsevier
More than 10 million death tolls in 2020 were reported as a result of heinous impact of
cancer, making it second most prime cause of death after cardiovascular diseases. In …

Acetylcholinesterase and Aβ aggregation inhibition by heterometallic ruthenium (II)–platinum (II) polypyridyl complexes

NA Vyas, SB Singh, AS Kumbhar, DS Ranade… - Inorganic …, 2018 - ACS Publications
Two heteronuclear ruthenium (II)–platinum (II) complexes [Ru (bpy) 2 (BPIMBp) PtCl2] 2+(3)
and [Ru (phen) 2 (BPIMBp) PtCl2] 2+(4), where bpy= 2, 2′-bipyridine, phen= 1, 10 …

A pH-sensitive DNA tetrahedron for targeted release of anthracyclines: binding properties investigation and cytotoxicity evaluation

T Weng, L Wang, X Zhang, Y Wu, Y Zhao… - International Journal of …, 2022 - Elsevier
The anticancer efficacy of chemotherapeutic agents can be enhanced by the loading of DNA
nanostructures, which is closely related to their interactions. This study achieved pH …

Recent progress in polynuclear ruthenium complex-based DNA binders/structural probes and anticancer agents

SQ Zhang, LH Gao, H Zhao… - Current Medicinal …, 2020 - ingentaconnect.com
Current Medicinal Chemistry Page 1 Current Medicinal Chemistry Current Medicinal
Chemistry ISSN: 0929-8673 eISSN: 1875-533X The International Journal for Timely In-depth …

A review on homo multinuclear anticancer Metallotherapuetics

S Pete, N Roy, P Paira - Inorganica Chimica Acta, 2021 - Elsevier
Cancer being the second most leading reason of death in the world, has been a challenge
to the chemists around the world in order to develop pertinent drugs which could pin down …

Interfering with DNA High‐Order Structures using Chiral Ruthenium (II) Complexes

S Zou, G Li, TW Rees, C Jin, J Huang… - … A European Journal, 2018 - Wiley Online Library
In this work, it was found that DNA can undergo B‐Z transformational changes and
compaction in the presence of DNA intercalators such as ruthenium (II) polypyridyl …

A new palladium-based antiproliferative agent: synthesis, characterization, computational calculations, cytotoxicity, and DNA binding properties

M Aminzadeh, H Mansouri-Torshizi, R Aleeshah… - Biometals, 2021 - Springer
A new palladium (II) complex entitled [Pd (phendione)(8Q)] NO3,(PdPQ), where phendione
is N, N-donor heterocyclic 1, 10-phenanthroline-5, 6-dion and 8Q is 8-hydroxyquinolinate …

Synthesis, characterization and DNA interactions of [Pt3 (TPymT) Cl3], the trinuclear platinum (II) complex of the TPymT ligand

T Marzo, D Cirri, L Ciofi, C Gabbiani, A Feis… - Journal of Inorganic …, 2018 - Elsevier
The triplatinum complex of the 2, 4, 6-Tris (2-pyrimidyl)-1, 3, 5-triazine ligand, Pt 3 TPymT
hereafter, has been prepared and characterized for the first time. NMR studies point out that …

Efficient DNA condensation by ruthenium (II) polypyridyl complexes containing triptycenyl functionalized 1, 10-phenanthroline

SS Bhat, VK Revankar, RV Pinjari, S Naveen… - New Journal of …, 2017 - pubs.rsc.org
A series of luminescent ruthenium (II) polypyridyl complexes containing an extended
aromatic moiety derived from triptycene and 1, 10-phenanthroline were synthesized and …