Fluorescence correlation spectroscopy (FCS) is a powerful technique for quantification of
molecular dynamics, and it has been widely applied in diverse fields, eg, biomedicine …

Ever since technologies enabled the characterization of eukaryotic plasma membranes,
heterogeneities in the distributions of its constituents were observed. Over the years this led …

Cells relay a plethora of extracellular signals to specific cellular responses by using only a
few second messengers, such as cAMP. To explain signaling specificity, cAMP-degrading …

Far-field optical microscopy using focused light is an important tool in a number of scientific
disciplines including chemical,(bio) physical and biomedical research, particularly with …

The interaction of lipids and proteins plays an important role in plasma membrane
bioactivity, and much can be learned from their diffusion characteristics. Here we present the …

The mechanisms by which the diffusion rate in the plasma membrane (PM) is regulated
remain unresolved, despite their importance in spatially regulating the reaction rates in the …

The translational motion of small molecules in cells appears to be suppressed compared to
what is observed in dilute solutions. Although, the rotation of small proteins is almost …

Fluorescence microscopy and spectroscopy data hold a wealth of information on the
investigated molecules, structures, or organisms. Nowadays, the same fluorescence data set …

Lipids and the membranes they form are fundamental building blocks of cellular life, and
their geometry and chemical properties distinguish membranes from other cellular …

The endoplasmic reticulum (ER) is an organelle that is responsible for many essential
subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like …