Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Cancer incidence increases with age and is a leading cause of death. Caloric restriction
(CR) confers benefits on health and survival and delays cancer. However, due to CR's …

Hypoxia is an environmental stressor that is instigated by low oxygen availability. It fuels the
progression of solid tumors by driving tumor plasticity, heterogeneity, stemness and genomic …

Autophagy is quintessential for the maintenance of cellular homeostasis in all eukaryotic
cells, explaining why both normal and malignant cells benefit from proficient autophagic …

Dietary restriction (DR) has long been viewed as the most robust nongenetic means to
extend lifespan and healthspan. Many aging-associated mechanisms are nutrient …

Cancer cells (CCs) predominantly use aerobic glycolysis (Warburg effect) for their
metabolism. This important characteristic of CCs represents a potential metabolic pathway to …

Despite great advances in treatment, cancer remains a leading cause of death worldwide.
Diet can greatly impact health, while caloric restriction and fasting have putative benefits for …

Recently, there has been an increase in the incidence of malignant tumors among the older
population. Moreover, there is an association between aging and cancer. During the …

Cancer is one of the most frequent causes of worldwide death and morbidity and is a major
public health problem. Although, there are several widely used treatment methods including …