[HTML][HTML] Search for New Compounds with Anti-Inflammatory Activity Among 1, 2, 4-Triazole Derivatives
T Glomb, J Minta, M Nowosadko, J Radzikowska… - Molecules, 2024 - mdpi.com
Compounds containing the 1, 2, 4-triazole moiety in their structure exhibit broad biological
activities. Many of these compounds demonstrate anti-inflammatory activity in vitro through …
activities. Many of these compounds demonstrate anti-inflammatory activity in vitro through …
Molecular hybrids of substituted phenylcarbamoylpiperidine and 1, 2, 4-triazole methylacetamide as potent 15-LOX inhibitors: Design, synthesis, DFT calculations and …
Inflammation is a multifaceted phenomenon triggered by potentially active mediators acutely
released arachidonic acid metabolites partially in lipoxygenase (LOX) pathway which are …
released arachidonic acid metabolites partially in lipoxygenase (LOX) pathway which are …
Exploration of 4-tolyl-5-(p-tolyloxymethyl)-4H-1, 2, 4-triazole thioethers as potent 15-LOX inhibitors supported by in vitro, in silico, MD simulation and DNA binding …
Inflammation is an intricate process exacerbated by the sequential release of lipid mediators
during arachidonic acid metabolism through the LOX and COX pathways. The inhibition of …
during arachidonic acid metabolism through the LOX and COX pathways. The inhibition of …