Advances in cobalt complexes as anticancer agents

CR Munteanu, K Suntharalingam - Dalton Transactions, 2015 - pubs.rsc.org
The evolution of resistance to traditional platinum-based anticancer drugs has compelled
researchers to investigate the cytostatic properties of alternative transition metal-based …

A concise review on cobalt Schiff base complexes as anticancer agents

K Kar, D Ghosh, B Kabi, A Chandra - Polyhedron, 2022 - Elsevier
Research on metal-based chemotherapeutics gained tremendous impetus after the
groundbreaking discovery of cisplatin and related complexes as potential anticancer agents …

Various coordination modes of new coumarin Schiff bases toward Cobalt (III) ion: synthesis, spectral characterization, in vitro cytotoxic activity, and investigation of …

K Giriraj, MS Mohamed Kasim… - Applied …, 2022 - Wiley Online Library
Four Co (III) complexes containing substituted acetyl coumarin Schiff bases have been
synthesized and structurally characterized using IR, UV–visible, 1H nuclear magnetic …

Harnessing the properties of cobalt coordination complexes for biological application

AK Renfrew, ES O'Neill, TW Hambley… - Coordination Chemistry …, 2018 - Elsevier
Cobalt is an essential metal that is found in very low abundance in the body and the
environment. Cobalt coordination complexes exhibit interesting redox and magnetic …

Cobalt derivatives as promising therapeutic agents

MC Heffern, N Yamamoto, RJ Holbrook… - Current opinion in …, 2013 - Elsevier
Inorganic complexes are versatile platforms for the development of potent and selective
pharmaceutical agents. Cobalt possesses a diverse array of properties that can be …

Metal‐mediated functionalization of natural peptides and proteins: Panning for bioconjugation gold

J Ohata, SC Martin, ZT Ball - Angewandte Chemie International …, 2019 - Wiley Online Library
Selective modification of natural proteins is a daunting methodological challenge and a
stringent test of selectivity and reaction scope. There is a continued need for new reactivity …

Synthesis, DNA binding and antibacterial activity of metal (II) complexes of a benzimidazole Schiff base

K Mahmood, W Hashmi, H Ismail, B Mirza, B Twamley… - Polyhedron, 2019 - Elsevier
Abstract The benzimidazole derivative (E)-2-((4-(1H-benzo [d] imidazol-2-yl) phenylimino)
methyl)-4-bromo phenol and the corresponding Zn (II), Ni (II), Cu (II), and Pd (II) complexes …

Bis (thiosemicarbazone) complexes of cobalt (III). Synthesis, characterization, and anticancer potential

AP King, HA Gellineau, JE Ahn, SN MacMillan… - Inorganic …, 2017 - ACS Publications
Nine bis (thiosemicarbazone)(BTSC) cobalt (III) complexes of the general formula [Co
(BTSC)(L) 2] NO3 were synthesized, where BTSC= diacetyl bis (thiosemicarbazone)(ATS) …

Inhibition of amyloid-β aggregation by cobalt (III) Schiff base complexes: a computational and experimental approach

A Iscen, CR Brue, KF Roberts, J Kim… - Journal of the …, 2019 - ACS Publications
Coordination complexes have emerged as prominent modulators of amyloid aggregation via
their interaction with the N-terminal histidine residues of amyloid-β (Aβ). Herein, we report …

[HTML][HTML] Revisiting metallodrugs for the treatment of skin cancers

CM Manzano, DH Nakahata, REF de Paiva - Coordination Chemistry …, 2022 - Elsevier
Metallodrugs were classically screened against skin cancer (either in vitro or in vivo) at the
peak of the development of platinum anticancer agents. New systematic studies appeared in …