Potential role of mitochondria-associated endoplasmic reticulum membrane proteins in diseases

H Mao, W Chen, L Chen, L Li - Biochemical pharmacology, 2022 - Elsevier
Mitochondria-associated endoplasmic reticulum membranes (MAMs) are dynamic
membrane coupling regions formed by the coupling of the mitochondrial outer membrane …

[HTML][HTML] Multi-target-directed cinnamic acid hybrids targeting Alzheimer's disease

A Drakontaeidi, E Pontiki - International journal of molecular sciences, 2024 - mdpi.com
Progressive cognitive decline in Alzheimer's disease (AD) is a growing challenge. Present
therapies are based on acetylcholinesterase inhibition providing only temporary relief …

Design, synthesis and evaluation of quinoline-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease

H Chen, J Mi, S Li, Z Liu, J Yang, R Chen… - Journal of Enzyme …, 2023 - Taylor & Francis
A series of novel quinoline-O-carbamate derivatives was rationally designed for treating
Alzheimer's disease (AD) by multi-target-directed ligands (MTDLs) strategy. The target …

Continuing progress in the field of two-dimensional correlation spectroscopy (2D-COS), part II. Recent noteworthy developments

Y Park, S Jin, I Noda, YM Jung - Spectrochimica Acta Part A: Molecular and …, 2023 - Elsevier
This comprehensive survey review compiles noteworthy developments and new concepts of
two-dimensional correlation spectroscopy (2D-COS) for the last two years. It covers review …

A novel reversible oxazole-based NIR fluorescent probe for Cu2+ and S2− ions detection

H Mei, C Yang, X Yang, Z Huang, P Cheng… - Journal of Molecular …, 2022 - Elsevier
In this study, we reported a novel oxazole-based NIR probe for the detection of Cu 2+ and S
2− ions sequentially in buffer solution. The probe showed a" turn-off" fluorescent response …

Copper (II) Schiff base complexes: Synthetic and medicinal perspective

P Kumari, M Choudhary, A Kumar, P Yadav… - Inorganic Chemistry …, 2023 - Elsevier
Schiff base ligands attract researchers due to their excellent coordination tendency with
various metals and medicinal importance. In ancient times, copper was mainly used as an …

A coumarin based ratiometric fluorescent probe for the detection of Cu2+ and mechanochromism as well as application in living cells and vegetables

L Deng, L Xue, Y Gao, S Fu, H Wang - Spectrochimica Acta Part A …, 2024 - Elsevier
In this paper, a novel coumarin-derived fluorescent probe NY was designed and
synthesized. NY displayed a significant ratiometric fluorescence response towards Cu 2+ in …

A hydrazone dual-functional fluorescent probe based on carbazole and coumarin groups for the detection of Cu2+ and ClO−: Application in live cell imaging and …

L Liu, C Guo, Q Zhang, P Xu, Y Cui, W Zhu… - … of Photochemistry and …, 2022 - Elsevier
A new hydrazone derivative LL3 based on carbazole and coumarin was prepared by the
condensation of 7-diethylaminocoumarin-3-carbohydrazide with 3-aldehyde-N-butyl …

Recent advances in the synthesis of nitrogen-containing heterocyclic compounds via multicomponent reaction and their emerging biological applications: a review

Mallappa, M Chahar, N Choudhary, KK Yadav… - Journal of the Iranian …, 2024 - Springer
Nitrogen-containing heterocyclic compounds (NCHCs) have an important role in the field of
medicinal chemistry due to their extensive biological activities and their prevalence in …

Sulfonamido-Pincer Complexes of Cu(II) and the Electrocatalysis of O2 Reduction

ML Skavenborg, MS Møller, S Mossin… - Inorganic …, 2023 - ACS Publications
Heteroleptic copper complexes of an asymmetrical pincer ligand containing a central
anionic sulfonamide donor (pyridine-2-yl-sulfonyl)(quinolin-8-yl)-amide (psq), which …