Although overall donation and transplantation activity is higher in Europe than on other
continents, differences between European countries in almost every aspect of …

The use of kidneys from controlled donation after circulatory death (DCD) donors has the
potential to markedly increase kidney transplants performed. However, this potential is not …

Objectives To assess the long term outcomes of transplantation using expanded criteria
donors (ECD; donors aged≥ 60 years or aged 50-59 years with vascular comorbidities) and …

Background. Delayed graft function is a frequent complication of kidney transplantation that
requires dialysis in the first week posttransplant. Materials and Methods. We searched for …

Warm ischemia time is a potentially modifiable insult to transplanted kidneys, but little is
known about its effect on long-term outcomes. Here we conducted a study of United States …

Importance In the United States, substantial disparities in access to kidney transplant exist
for wait-listed candidates with end-stage renal disease. The implications of transplant …

Graft inflammation impairs the induction of solid organ transplant tolerance and enhances
acute and chronic rejection. Elucidating the mechanisms by which inflammation is induced …

Advances in surgical procedures, technology, and immune suppression have transformed
organ transplantation. However, the metabolic changes that occur during organ retrieval …

Cold ischemia triggers a cascade of noxious effects, which are amplified by restoration of
blood supply reperfusion. These injuries generate inflammatory and immune responses that …

Acute tubular necrosis causes a loss of renal function, which clinically presents as acute
kidney failure (AKI). The biochemical signaling pathways that trigger necrosis have been …