Initial SRS for patients with 5 to 15 brain metastases: results of a multi-institutional experience

RT Hughes, AH Masters, ER McTyre, MK Farris… - International Journal of …, 2019 - Elsevier
Purpose Several studies evaluating stereotactic radiosurgery (SRS) for patients with> 4
brain metastases (BM) demonstrated similar outcomes after treatment of 1, 2 to 4, and 5 to …

Stereotactic radiosurgery (SRS) for brain metastases: a systematic review

C Nieder, AL Grosu, LE Gaspar - Radiation Oncology, 2014 - Springer
In many patients with brain metastases, the primary therapeutic aim is symptom palliation
and maintenance of neurologic function, but in a subgroup, long-term survival is possible …

Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment

Q Song, J Ruiz, F Xing, HW Lo, L Craddock… - Communications …, 2023 - nature.com
Brain metastases is the most common intracranial tumor and account for approximately 20%
of all systematic cancer cases. It is a leading cause of death in advanced-stage cancer …

Differentiation between radiation necrosis and tumor progression using chemical exchange saturation transfer

H Mehrabian, KL Desmond, H Soliman, A Sahgal… - Clinical Cancer …, 2017 - AACR
Purpose: Stereotactic radiosurgery (SRS) is a common treatment used in patients with brain
metastases and is associated with high rates of local control, however, at the risk of radiation …

Brain metastasis velocity: a novel prognostic metric predictive of overall survival and freedom from whole-brain radiation therapy after distant brain failure following …

M Farris, ER McTyre, CK Cramer, R Hughes… - International Journal of …, 2017 - Elsevier
Purpose Prior statistical models attempted to identify risk factors for time to distant brain
failure (DBF) or time to salvage whole-brain radiation therapy (WBRT) to predict the benefit …

Advanced magnetic resonance imaging techniques in management of brain metastases

H Mehrabian, J Detsky, H Soliman, A Sahgal… - Frontiers in …, 2019 - frontiersin.org
Brain metastases are the most common intracranial tumors and occur in 20–40% of all
cancer patients. Lung cancer, breast cancer, and melanoma are the most frequent primary …

Local control outcomes for combination of stereotactic radiosurgery and immunotherapy for non-small cell lung cancer brain metastases

M Abdulhaleem, H Johnston, R D'Agostino Jr… - Journal of Neuro …, 2022 - Springer
Background Previous series have demonstrated CNS activity for immune checkpoint
inhibitors, yet no prior data exists regarding whether this activity can improve outcomes of …

Radiomics as prognostic factor in brain metastases treated with Gamma Knife radiosurgery

CY Huang, CC Lee, HC Yang, CJ Lin, HM Wu… - Journal of Neuro …, 2020 - Springer
Abstract Purpose Gamma Knife radiosurgery (GKRS) is a non-invasive procedure for the
treatment of brain metastases. This study sought to determine whether radiomic features of …

Multi-omics analysis of brain metastasis outcomes following craniotomy

J Su, Q Song, S Qasem, S O'Neill, J Lee… - Frontiers in …, 2021 - frontiersin.org
Background The incidence of brain metastasis continues to increase as therapeutic
strategies have improved for a number of solid tumors. The presence of brain metastasis is …

Prognostic and predictive factors in patients with brain metastases from solid tumors: a review of published nomograms

C Nieder, MP Mehta, H Geinitz, AL Grosu - Critical reviews in oncology …, 2018 - Elsevier
Objective To review published nomograms that predict endpoints such as overall survival
(OS) or risk of intracranial relapse in patients with brain metastases from solid tumors …