[HTML][HTML] Harnessing reactive oxygen/nitrogen species and inflammation: Nanodrugs for liver injury

M Liu, Q Huang, Y Zhu, L Chen, Y Li, Z Gong, K Ai - Materials Today Bio, 2022 - Elsevier
Overall, 12% of the global population (800 million) suffers from liver disease, which causes 2
million deaths every year. Liver injury involving characteristic reactive oxygen/nitrogen …

Emerging applications and prospects of NFκB decoy oligodeoxynucleotides in managing respiratory diseases

JK Datsyuk, KR Paudel, R Rajput, S Kokkinis… - Chemico-biological …, 2023 - Elsevier
Chronic respiratory diseases like asthma and Chronic Obstructive Pulmonary Disease
(COPD) have been a burden to society for an extended period. Currently, there are only …

Recent trends of NFκB decoy oligodeoxynucleotide-based nanotherapeutics in lung diseases

M Mehta, KR Paudel, SD Shukla, VSRR Allam… - Journal of Controlled …, 2021 - Elsevier
Nuclear factor κB (NFκB) is a unique protein complex that plays a major role in lung
inflammation and respiratory dysfunction. The NFκB signaling pathway, therefore becomes …

NANOG decoy oligodeoxynucleotide–encapsulated niosomes nanocarriers: a promising approach to suppress the metastatic properties of U87 human glioblastoma …

M Gharbavi, B Johari, E Rismani… - ACS Chemical …, 2020 - ACS Publications
Recently, advances in the synthesis and development of multifunctional nanoparticle
platforms have opened up great opportunities and advantages for specifically targeted …

Decoy oligodeoxynucleotides: A promising therapeutic strategy for inflammatory skin disorders

M Mahjoubin-Tehran, S Rezaei, S Karav… - Human Immunology, 2024 - Elsevier
Chronic inflammatory skin conditions such as psoriasis and atopic dermatitis (AD) impose a
significant burden on both the skin and the overall well-being of individuals, leading to a …

Composition, preparation methods, and applications of nanoniosomes as codelivery systems: a review of emerging therapies with emphasis on cancer

M Roostaee, A Derakhshani, H Mirhosseini… - Nanoscale, 2024 - pubs.rsc.org
Nanoniosome-based drug codelivery systems have become popular therapeutic
instruments, demonstrating tremendous promise in cancer therapy, infection treatment, and …

Advancing Cancer Treatments: The role of oligonucleotides-based therapies in driving progress

B Dume, E Licarete, M Banciu - Molecular Therapy-Nucleic Acids, 2024 - cell.com
Although recent advancements in cancer immunology have resulted in the approval of
numerous immunotherapies, minimal progress has been observed in addressing hard-to …

Blocking M2-like macrophage polarization using decoy oligodeoxynucleotide-based gene therapy prevents immune evasion for pancreatic cancer treatment

CJ Chen, HC Wang, YC Hou, YY Wu, CC Shieh… - Molecular Cancer …, 2024 - AACR
M2-like macrophages exhibit immunosuppressive activity and promote pancreatic cancer
progression. Reactive oxygen species (ROS) affect macrophage polarization; however, the …

[HTML][HTML] Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation

S Rezaei, MHJN Abadi, MJ Bazyari, A Jalili… - Iranian Journal of …, 2024 - ncbi.nlm.nih.gov
Objective (s): MicroRNAs, which are micro-coordinators of gene expression, have been
recently investigated as a potential treatment for cancer. The study used computational …

Decoy technology as a promising therapeutic tool for atherosclerosis

M Mahjoubin-Tehran, Y Teng, A Jalili… - International journal of …, 2021 - mdpi.com
Cardiovascular diseases (CVDs) have been classified into several types of disease, of
which atherosclerosis is the most prevalent. Atherosclerosis is characterized as an …