Trans-spinal electrical stimulation therapy for functional rehabilitation after spinal cord injury

MA Rahman, NS Tharu, SM Gustin, YP Zheng… - Journal of clinical …, 2022 - mdpi.com
Spinal cord injury (SCI) is one of the most debilitating injuries in the world. Complications
after SCI, such as respiratory issues, bowel/bladder incontinency, pressure ulcers …

Cortical and subcortical effects of transcutaneous spinal cord stimulation in humans with tetraplegia

FD Benavides, HJ Jo, H Lundell… - Journal of …, 2020 - Soc Neuroscience
An increasing number of studies supports the view that transcutaneous electrical stimulation
of the spinal cord (TESS) promotes functional recovery in humans with spinal cord injury …

The plasticity of nerve fibers: The prolonged effects of polarization of afferent fibers

E Jankowska, I Hammar - Journal of Neurophysiology, 2021 - journals.physiology.org
The review surveys various aspects of the plasticity of nerve fibers, in particular the
prolonged increase in their excitability evoked by polarization, focusing on a long-lasting …

Multisite Hebbian plasticity restores function in humans with spinal cord injury

HJ Jo, E Kizziar, S Sangari, D Chen… - Annals of …, 2023 - Wiley Online Library
Objective Spinal cord injury (SCI) damages synaptic connections between corticospinal
axons and motoneurons of many muscles, resulting in devastating paralysis. We …

Feasibility and utility of transcutaneous spinal cord stimulation combined with walking-based therapy for people with motor incomplete spinal cord injury

LV McHugh, AA Miller, KA Leech, C Salorio… - Spinal cord series and …, 2020 - nature.com
Study design Prospective case series. Objectives To evaluate the feasibility and preliminary
efficacy of combining transcutaneous spinal cord stimulation (TSCS) with walking-based …

Spinal direct current stimulation (tsDCS) in hereditary spastic paraplegias (HSP): A sham-controlled crossover study

G Ardolino, T Bocci, M Nigro, M Vergari… - The journal of spinal …, 2021 - Taylor & Francis
Objective: Hereditary spastic paraplegia (HSP) represents a heterogeneous group of
neurodegenerative diseases characterized by progressive spasticity and lower limb …

Corticospinal excitability and voluntary activation of the quadriceps muscle is not affected by a single session of anodal transcutaneous spinal direct current …

G Stępień, W Jelonek, S Goodall… - European Journal of …, 2024 - Wiley Online Library
The aim of the present study was to determine if anodal transcutaneous spinal direct current
stimulation (tsDCS) affects corticospinal excitability (CSE) and voluntary activation (VA) of …

Adapting human-based transcutaneous spinal cord stimulation to develop a clinically relevant animal model

DC Malloy, M Knikou, MP Côté - Journal of clinical medicine, 2022 - mdpi.com
Transcutaneous spinal cord stimulation (tSCS) as a neuromodulatory strategy has received
great attention as a method to promote functional recovery after spinal cord injury (SCI) …

Trans-Spinal Direct Current Stimulation in Neurological Disorders: A systematic review

JJ Fernández-Pérez, D Serrano-Muñoz… - Journal of Neurologic …, 2024 - journals.lww.com
Background and Purpose: Trans-spinal direct current stimulation (tsDCS) is a noninvasive
stimulation technique that applies direct current stimulation over spinal levels. However, the …

Repeated cathodal transspinal pulse and direct current stimulation modulate cortical and corticospinal excitability differently in healthy humans

LM Murray, M Knikou - Experimental brain research, 2019 - Springer
Noninvasive transspinal stimulation of the thoracolumbar region, where leg motor circuits
reside, produces prominent plasticity of brain and spinal cord circuits. However …