Keeping your brain in balance: Homeostatic regulation of network function

W Wen, GG Turrigiano - Annual Review of Neuroscience, 2024 - annualreviews.org
To perform computations with the efficiency necessary for animal survival, neocortical
microcircuits must be capable of reconfiguring in response to experience, while carefully …

TNF-Mediated Homeostatic Synaptic Plasticity: From in vitro to in vivo Models

R Heir, D Stellwagen - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Since it was first described almost 30 years ago, homeostatic synaptic plasticity (HSP) has
been hypothesized to play a key role in maintaining neuronal circuit function in both …

Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies

F Cicconardi, E Milanetti, EC Pinheiro de Castro… - Nature …, 2023 - nature.com
Heliconius butterflies, a speciose genus of Müllerian mimics, represent a classic example of
an adaptive radiation that includes a range of derived dietary, life history, physiological and …

Active zone compaction correlates with presynaptic homeostatic potentiation

A Mrestani, M Pauli, P Kollmannsberger, F Repp… - Cell Reports, 2021 - cell.com
Neurotransmitter release is stabilized by homeostatic plasticity. Presynaptic homeostatic
potentiation (PHP) operates on timescales ranging from minute-to life-long adaptations and …

Miniature neurotransmission is required to maintain Drosophila synaptic structures during ageing

S Banerjee, S Vernon, W Jiao, BJ Choi, E Ruchti… - Nature …, 2021 - nature.com
The decline of neuronal synapses is an established feature of ageing accompanied by the
diminishment of neuronal function, and in the motor system at least, a reduction of …

A glutamate receptor C-tail recruits CaMKII to suppress retrograde homeostatic signaling

S Perry, Y Han, C Qiu, C Chien, P Goel… - Nature …, 2022 - nature.com
Presynaptic homeostatic plasticity (PHP) adaptively enhances neurotransmitter release
following diminished postsynaptic glutamate receptor (GluR) functionality to maintain …

Structural and functional synaptic plasticity induced by convergent synapse loss in the Drosophila neuromuscular circuit

Y Wang, M Lobb-Rabe, J Ashley, V Anand… - Journal of …, 2021 - Soc Neuroscience
Throughout the nervous system, the convergence of two or more presynaptic inputs on a
target cell is commonly observed. The question we ask here is to what extent converging …

[HTML][HTML] Excess glutamate release triggers subunit-specific homeostatic receptor scaling

Y Han, P Goel, J Chen, S Perry, N Tran, S Nishimura… - Cell reports, 2023 - cell.com
Ionotropic glutamate receptors (GluRs) are targets for modulation in Hebbian and
homeostatic synaptic plasticity and are remodeled by development, experience, and …

Synaptic properties and plasticity mechanisms of invertebrate tonic and phasic neurons

NA Aponte-Santiago, JT Littleton - Frontiers in Physiology, 2020 - frontiersin.org
Defining neuronal cell types and their associated biophysical and synaptic diversity has
become an important goal in neuroscience as a mechanism to create comprehensive brain …

Synaptic plasticity induced by differential manipulation of tonic and phasic motoneurons in Drosophila

NA Aponte-Santiago, KG Ormerod… - Journal of …, 2020 - Soc Neuroscience
Structural and functional plasticity induced by neuronal competition is a common feature of
developing nervous systems. However, the rules governing how postsynaptic cells …