[HTML][HTML] Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemic
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the
COVID-19 pandemic, it has become one of the most therapeutically targeted human …
COVID-19 pandemic, it has become one of the most therapeutically targeted human …
COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options
LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), continues to spread globally despite the worldwide …
syndrome coronavirus 2 (SARS‐CoV‐2), continues to spread globally despite the worldwide …
Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review
Colchicine is an ancient herbal drug derived from Colchicum autumnale. It was first used to
treat familial Mediterranean fever and gout. Based on its unique efficacy as an anti …
treat familial Mediterranean fever and gout. Based on its unique efficacy as an anti …
Hypertension, a moving target in COVID-19: current views and perspectives
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) associates with a considerable high rate of mortality and …
coronavirus 2 (SARS-CoV-2) associates with a considerable high rate of mortality and …
Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences
Coronavirus disease 2019 (COVID-19) causes persistent endothelial inflammation, lung,
cardiovascular, kidney and neurological complications, and thromboembolic phenomena of …
cardiovascular, kidney and neurological complications, and thromboembolic phenomena of …
Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients
TW Kragstrup, HS Singh, I Grundberg, ALL Nielsen… - PloS one, 2021 - journals.plos.org
Aims Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to angiotensin
converting enzyme 2 (ACE2) enabling entrance of the virus into cells and causing the …
converting enzyme 2 (ACE2) enabling entrance of the virus into cells and causing the …
Dysregulation of ACE (angiotensin-converting enzyme)-2 and renin-angiotensin peptides in SARS-CoV-2 mediated mortality and end-organ injuries
ACE (angiotensin-converting enzyme)-2 as the target for SARS-CoV-2 also negatively
regulates the renin-angiotensin system. Pathological activation of ADAM17 (A disintegrin …
regulates the renin-angiotensin system. Pathological activation of ADAM17 (A disintegrin …
Low vitamin D levels predict outcomes of COVID-19 in patients with both severe and non-severe disease at hospitalization
Purpose Low vitamin D in COVID-19 have been related to worse outcomes. However, most
of the studies conducted so far were not-controlled and retrospective, including biases …
of the studies conducted so far were not-controlled and retrospective, including biases …
Precision medicine for cardiometabolic disease: a framework for clinical translation
Cardiometabolic disease is a major threat to global health. Precision medicine has great
potential to help to reduce the burden of this common and complex disease cluster, and to …
potential to help to reduce the burden of this common and complex disease cluster, and to …
ACE2 Shedding and the Role in COVID-19
J Wang, H Zhao, Y An - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Angiotensin converting enzyme 2 (ACE2), a transmembrane glycoprotein, is an important
part of the renin-angiotensin system (RAS). In the COVID-19 epidemic, it was found to be the …
part of the renin-angiotensin system (RAS). In the COVID-19 epidemic, it was found to be the …