Background: Previous studies examining the association of apolipoprotein E (APOE) gene
polymorphism with the risk of ischemic stroke (IS) have yielded conflicting results. Therefore …

Background Ischaemic stroke in persons of European descent has a genetic basis, but
whether the stroke-susceptibility alleles, the strength of any association, and the extent of …

Stroke is a heterogeneous multifactorial disease and is thought to have a polygenic basis.
Case–control studies on gene sequence variations have identified a number of potential …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has rapidly spread
worldwide, posing a global medical concern. This novel RNA virus enters cells by binding to …

The genetics of stroke : Current Opinion in Lipidology The genetics of stroke : Current Opinion in
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Background: The renin–angiotensin system is involved in the development of hypertension,
atherosclerosis and cardiovascular disease. We studied the association between the M235T …

Tumor necrosis factor (TNF) is an important cytokine in the inflammation process of
atherosclerosis. Two biallelic polymorphisms in the TNF-α (TNF-α-308) and TNF-β (TNF-β+ …

Objective–The association of renin C‐4063T and angiotensinogen (AGT) T174M, AGT
M235T and AGT A‐6G polymorphisms with ischemic stroke of atherosclerotic etiology was …

Recent observations revealed a novel role of angiotensin-converting enzyme 2 and the
angiotensin II type-1 receptor (AT1R) in lung injury, thereby extending knowledge about the …

The angiotensinogen (AGT) gene M235T polymorphism has been reported to be associated
with myocardial infarction (MI) and brain infarction (BI), but the results remain inconclusive …