Kidneys are central in the regulation of multiple physiological functions, such as removal of
metabolic wastes and toxins, maintenance of electrolyte and fluid balance, and control of pH …

Metabolic acidosis, defined as a plasma or serum bicarbonate concentration< 22 mmol/L, is
a frequent consequence of chronic kidney disease (CKD) and occurs in~ 10–30% of …

Background Individuals with CKD are at a higher risk of cardiovascular morbidity and
mortality. Acidosis is positively correlated with CKD progression and elevated systolic BP …

Background: In patients with chronic kidney disease (CKD), impaired kidney acid excretion
leads to the onset of metabolic acidosis (MA). However, the evidence is not yet conclusive …

Hyperkalaemia is a common electrolyte imbalance with potentially serious short-, medium-
and long-term consequences on morbidity and mortality rates and the use of national health …

Chronic kidney disease (CKD) affects approximately 10–13% of the population worldwide
and halting its progression is a major clinical challenge. Metabolic acidosis is both a …

Metabolic acidosis is a frequent complication in non-transplant chronic kidney disease
(CKD) and after kidney transplantation. It occurs when net endogenous acid production …

Chronic kidney disease (CKD) is characterized by progressive reduction in kidney function
and treatments aiming at stabilizing or slowing its progression may avoid or delay the …

Background: No study has explored the limitations of current long-term management of
hyperkalemia (HK) in outpatient CKD clinics. Methods: We evaluated the association …

Introduction We investigated the efficacy and safety of oral sodium bicarbonate in kidney-
transplant recipients and non-transplant patients with chronic kidney disease (CKD), which …