Neuropharmacological modulation of N-methyl-D-aspartate, noradrenaline and endocannabinoid receptors in fear extinction learning: Synaptic transmission and …

S Battaglia, C Di Fazio, CM Vicario… - International Journal of …, 2023 - mdpi.com
Learning to recognize and respond to potential threats is crucial for survival. Pavlovian
threat conditioning represents a key paradigm for investigating the neurobiological …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Neurobiological interactions between stress and the endocannabinoid system

M Morena, S Patel, JS Bains, MN Hill - Neuropsychopharmacology, 2016 - nature.com
Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

The endocannabinoid system and the brain

R Mechoulam, LA Parker - Annual review of psychology, 2013 - annualreviews.org
The psychoactive constituent in cannabis, Δ9-tetrahydrocannabinol (THC), was isolated in
the mid-1960s, but the cannabinoid receptors, CB1 and CB2, and the major endogenous …

Stress and glucocorticoid receptor-dependent mechanisms in long-term memory: from adaptive responses to psychopathologies

C Finsterwald, CM Alberini - Neurobiology of learning and memory, 2014 - Elsevier
A proper response against stressors is critical for survival. In mammals, the stress response
is primarily mediated by secretion of glucocorticoids via the hypothalamic–pituitary …

The acute effects of cannabinoids on memory in humans: a review

M Ranganathan, DC D'Souza - Psychopharmacology, 2006 - Springer
Rationale Cannabis is one of the most frequently used substances. Cannabis and its
constituent cannabinoids are known to impair several aspects of cognitive function, with the …

Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study

CJA Morgan, G Schafer, TP Freeman… - The British Journal of …, 2010 - cambridge.org
BackgroundThe two main constituents of cannabis, cannabidiol and δ9-
tetrahydrocannabinol (THC), have opposing effects both pharmacologically and …

Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory

P Campolongo, B Roozendaal… - Proceedings of the …, 2009 - National Acad Sciences
Extensive evidence indicates that the basolateral complex of the amygdala (BLA) modulates
the consolidation of memories for emotionally arousing experiences, an effect that involves …

Cannabinoid regulation of fear and anxiety: an update

EP Papagianni, CW Stevenson - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review Anxiety-and trauma-related disorders are prevalent and
debilitating mental illnesses associated with a significant socioeconomic burden. Current …

A review of behavioral methods for the evaluation of cognitive performance in animal models: current techniques and links to human cognition

M Ghafarimoghadam, R Mashayekh, M Gholami… - Physiology & …, 2022 - Elsevier
Introduction: Memory is defined as the ability to store, maintain and retrieve information.
Learning is the acquisition of information that changes behavior and memory. Stress …