Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …

Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

While immune checkpoint inhibitors (ICIs) have ushered in major changes in standards of
care for many solid tumor malignancies, primary and acquired resistance is common …

Assessment of the immune response to tumors is growing in importance as the prognostic
implications of this response are increasingly recognized, and as immunotherapies are …

Tumours often contain B cells and plasma cells but the antigen specificity of these
intratumoral B cells is not well understood,,,,,,–. Here we show that human papillomavirus …

Infections with human papillomavirus (HPV) are common and transmitted by direct contact.
Although the great majority of infections resolve within 2 years, 13 phylogenetically related …

Head and neck squamous cell carcinoma (HNSCC) comprises a heterogeneous group of
tumors that arise from the squamous epithelium of the oral cavity, oropharynx, larynx and …

High-risk human papillomavirus (HPV) is now recognised as the principal cause of the
increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some …

Interactions between immune and malignant cells have been known to have clinical
relevance for decades. The potential for immune control is now being therapeutically …

The nature and extent of immune cell infiltration into solid tumours are key determinants of
therapeutic response. Here, using a DNA methylation-based approach to tumour cell …