Aspergillosis is a fungal infection caused by various species of Aspergillus, most notably A.
fumigatus. This fungus causes a spectrum of diseases, including allergic bronchopulmonary …

Most fungi are capable of disseminating into the central nervous system (CNS) commonly
being observed in immunocompromised hosts. Microglia play a critical role in responding to …

Invasive aspergillosis caused by Aspergillus species (Aspergillus fumigatus, A. flavus, and
A. terreus) is life-threatening infections in immunocompromised patients. Understanding the …

Aspergillus species encompass a variety of infections, ranging from invasive aspergillosis to
allergic conditions, contingent upon the immune status of the host. In this spectrum …

Exposure of immunosuppressed individuals to the opportunistic fungal pathogen Aspergillus
fumigatus may result in invasive pulmonary aspergillosis (IPA), which can lead to the …

With the increasing numbers of immunocompromised hosts, Aspergillus fumigatus emerges
as a lethal opportunistic fungal pathogen. Understanding innate and acquired immunity …

Pentraxin-3 (PTX-3) protein is an evolutionary conserved protein that acts as a soluble
pattern-recognition receptor for pathogens and plays important role in innate immune …

Delivery of poorly permeable drugs across the blood-brain barrier (BBB) is a great challenge
in the treatment of ischemic stroke. In order to construct a suitable delivery system for this …

Despite increasing associated mortality and morbidity, the diagnosis of fungal infections,
especially with Aspergillus fumigatus (A. fumigatus), remains challenging. Based on known …

A great challenge to the therapy of ischemic stroke is the poor physicochemical properties
and inability of the drug to cross the blood–brain barrier (BBB). In order to overcome these …