The role of gut microbiota in tumor immunotherapy

M Wu, J Bai, C Ma, J Wei, X Du - Journal of Immunology …, 2021 - Wiley Online Library
Tumor immunotherapy is the fourth therapy after surgery, chemotherapy, and radiotherapy. It
has made great breakthroughs in the treatment of some epithelial tumors and hematological …

Hyperglycemia-driven signaling bridges between diabetes and cancer

S Ghareghomi, P Arghavani, M Mahdavi… - Biochemical …, 2024 - Elsevier
Growing epidemiological evidence indicates an association between obesity, type 2
diabetes, and certain cancers, suggesting the existence of common underlying mechanisms …

A study on the association between gut microbiota, inflammation, and type 2 diabetes

N Liu, X Yan, B Lv, Y Wu, X Hu, C Zheng, S Tao… - Applied Microbiology …, 2024 - Springer
Type 2 diabetes mellitus (T2DM) was reported to be associated with impaired immune
response and alterations in microbial composition and function. However, the underlying …

Metabolic and hormonal remodeling of colorectal cancer cell signalling by diabetes

M Gutiérrez-Salmerón, SR Lucena… - Endocrine-Related …, 2021 - erc.bioscientifica.com
The existence of molecular links that facilitate colorectal cancer (CRC) development in the
population with type 2 diabetes (T2D) is supported by substantial epidemiological evidence …

Causal linkage between type 2 diabetes mellitus and inflammatory bowel disease: an integrated Mendelian randomization study and bioinformatics analysis

X Xiao, X Wu, L Yi, F You, X Li, C Xiao - Frontiers in Endocrinology, 2024 - frontiersin.org
Background Observational studies have indicated associations between type 2 diabetes
mellitus (T2DM) and both colorectal cancer (CRC) and inflammatory bowel disease (IBD) …

Gut microbiota and colorectal cancer risk factors

H Feizi, MA Rezaee, R Ghotaslou… - Current …, 2023 - ingentaconnect.com
Colorectal cancer is a type of gut cancer originating either from the rectum or colon. Genetic
and environmental factors, such as the gut microbiome, play pivotal roles in colorectal …

Autoimmune and metabolic diseases and the risk of early-onset colorectal cancer, a Nationwide nested case–control study

E Lundqvist, IH Myrberg, SE Boman, D Saraste… - Cancers, 2023 - mdpi.com
Simple Summary Early onset of colorectal cancer (EOCRC) is increasing in developed
countries. The aim was to investigate autoimmune and metabolic conditions as risk factors …

High-throughput sequencing reveals crebanine inhibits colorectal cancer by modulating Tregs immune prognostic target genes

J Xu, L Huang, Y Sha, C Mo, W Gong, X Tian, X Hou… - Oncologie, 2024 - degruyter.com
Objectives Crebanine, an alkaloid exhibiting sedative, anti-inflammatory, and anticancer
properties, remains unexplored in terms of its anticancer potential against colorectal cancer …

Cancer in diabetes: Who is who?

C García-Jiménez, JM García-Martínez… - … of Diabetes Mellitus, 2024 - Elsevier
The diabetic population is at increased risk of suffering certain site-specific cancers. The
nature of the connections linking the appearance of cancer to diabetes and vice versa is …

[HTML][HTML] 基于LPS/TLR4/NF-κB 信号通路探讨中药干预糖尿病慢性炎症状态研究进展

孙明秀 - Advances in Clinical Medicine, 2023 - hanspub.org
随着高脂饮食, 运动量减少等不良生活习惯的形成, 糖尿病患者数量与日俱增,
已成为全球严重的公共卫生问题, 为缓解社会经济负担和医疗压力, 探析糖尿病的有效治疗手段 …