[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation

JL Ables, K Park, I Ibañez–Tallon - Pharmacological research, 2023 - Elsevier
Over the last decade, the understanding of the habenula has rapidly advanced from being
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …

Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects

F Pistillo, F Clementi, M Zoli, C Gotti - Progress in neurobiology, 2015 - Elsevier
Cigarette smoking is currently the leading cause of preventable deaths and disability
throughout the world, being responsible for about five million premature deaths/year …

Basic science of electronic cigarettes: assessment in cell culture and in vivo models

PS Hiemstra, R Bals - Respiratory research, 2016 - Springer
Electronic cigarettes (e-cigarettes, ECIGs) were introduced into the market a decade ago as
an alternative to tobacco smoking. Whether ECIGs are safe and whether they qualify as …

An Ethyl Acetate Fraction of Moringa oleifera Lam. Inhibits Human Macrophage Cytokine Production Induced by Cigarette Smoke

N Kooltheat, R Pankla Sranujit, P Chumark, P Potup… - Nutrients, 2014 - mdpi.com
Moringa oleifera Lam.(MO) has been reported to harbor anti-oxidation and anti-inflammatory
activity and useful in the treatment of inflammatory diseases. However, despite these …

Nicotine e-cigarette vapor inhalation effects on nicotine & cotinine plasma levels and somatic withdrawal signs in adult male Wistar rats

C Montanari, LK Kelley, TM Kerr, M Cole… - Psychopharmacology, 2020 - Springer
Rationale Non-contingent chronic nicotine exposure procedures have evolved rapidly in
recent years, culminating in electronic nicotine delivery systems (ENDS or e-cigarettes) to …

Rodent models for nicotine withdrawal

R Chellian, A Behnood-Rod… - Journal of …, 2021 - journals.sagepub.com
Background: Animal models are critical to improve our understanding of the neuronal
mechanisms underlying nicotine withdrawal. Nicotine dependence in rodents can be …

Validation of a nicotine vapor self-administration model in rats with relevance to electronic cigarette use

LC Smith, M Kallupi, L Tieu, K Shankar… - …, 2020 - nature.com
The debate about electronic cigarettes is dividing healthcare professionals, policymakers,
manufacturers, and communities. A key limitation in our understanding of the cause and …

The impact of chronic daily nicotine exposure and its overnight withdrawal on the structure of anxiety-related behaviors in rats: Role of the lateral habenula

M Casarrubea, C Davies, M Pierucci… - Progress in Neuro …, 2021 - Elsevier
Tobacco smoking is a serious health problem worldwide and a leading cause of mortality.
Nicotine, the addictive component of tobacco, affects a range of emotional responses …

Effect of chronic vapor nicotine exposure on affective and cognitive behavior in male mice

LB Murdaugh, C Miliano, I Chen, CL Faunce… - Scientific Reports, 2024 - nature.com
Nicotine use is a leading cause of preventable deaths worldwide, and most of those who
attempt to quit will relapse. While electronic cigarettes and other electronic nicotine delivery …

Brain derived neurotrophic factor (BDNF), its tyrosine kinase receptor B (TrkB) and nicotine

R Machaalani, H Chen - Neurotoxicology, 2018 - Elsevier
Nicotine is the major neurotoxicant in cigarettes that affects many transmitter systems within
the brain as well as other factors, including the growth factors. Brain derived neurotrophic …