Macrophages in immunoregulation and therapeutics

S Chen, AFUH Saeed, Q Liu, Q Jiang, H Xu… - … and Targeted Therapy, 2023 - nature.com
Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

Application of ultrasound for muscle assessment in sarcopenia: 2020 SARCUS update

S Perkisas, S Bastijns, S Baudry, J Bauer… - European geriatric …, 2021 - Springer
Purpose In 2018, the SARCUS working group published a first article on the standardization
of the use of ultrasound to assess muscle. Recommendations were made for patient …

Genetic insights into biological mechanisms governing human ovarian ageing

KS Ruth, FR Day, J Hussain, A Martínez-Marchal… - Nature, 2021 - nature.com
Reproductive longevity is essential for fertility and influences healthy ageing in women,, but
insights into its underlying biological mechanisms and treatments to preserve it are limited …

Elevated LDL cholesterol and increased risk of myocardial infarction and atherosclerotic cardiovascular disease in individuals aged 70–100 years: a contemporary …

MB Mortensen, BG Nordestgaard - The Lancet, 2020 - thelancet.com
Background Findings of historical studies suggest that elevated LDL cholesterol is not
associated with increased risk of myocardial infarction and atherosclerotic cardiovascular …

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a …

GBD Collaborators - 2018 - figshare.le.ac.uk
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017
(GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years …

AMP-activated protein kinase: the current landscape for drug development

GR Steinberg, D Carling - Nature reviews Drug discovery, 2019 - nature.com
Since the discovery of AMP-activated protein kinase (AMPK) as a central regulator of energy
homeostasis, many exciting insights into its structure, regulation and physiological roles …

Prevalence and determinants of COPD in Spain: EPISCAN II

JB Soriano, I Alfageme, M Miravitlles… - Archivos de …, 2021 - Elsevier
Background Two previous national epidemiological studies, IBERPOC in 1997 and
EPISCAN in 2007, determined the COPD burden in Spain. Changes in demographics and …

[HTML][HTML] The burden of OA-health services and economics

VP Leifer, JN Katz, E Losina - Osteoarthritis and cartilage, 2022 - Elsevier
Osteoarthritis (OA) is a highly prevalent and disabling condition that affects over 7% of
people globally (528 million people). Prevalence levels are even higher in countries with …

Social support in the general population: standardization of the Oslo social support scale (OSSS-3)

RD Kocalevent, L Berg, ME Beutel, A Hinz, M Zenger… - BMC psychology, 2018 - Springer
Background The objectives of the study were to generate normative data for the Oslo Social
Support Scale (OSSS-3) for different age groups for men and women and to further …

[HTML][HTML] Factors determining the success and failure of eHealth interventions: systematic review of the literature

C Granja, W Janssen, MA Johansen - Journal of medical Internet research, 2018 - jmir.org
Background eHealth has an enormous potential to improve healthcare cost, effectiveness,
and quality of care. However, there seems to be a gap between the foreseen benefits of …