Aims Chronic kidney disease (CKD) and worsening renal function (WRF) have been
associated with poor outcome in heart failure (HF). Methods and results Articles were …

Heart and kidney are closely related in the clinical syndrome of heart failure (HF). It is now
sufficiently clear that renal dysfunction occurs frequently in all phenotypes of HF, and when …

Appropriate interpretation of changes in markers of kidney function is essential during the
treatment of acute and chronic heart failure. Historically, kidney function was primarily …

Novel pharmacologic treatment options reduce mortality and morbidity in a cost‐effective
manner in patients with heart failure (HF). Undisputedly, the effective implementation of …

It is well established that a large number of patients with acute decompensated heart failure
present with various degrees of heart and kidney dysfunction usually primary disease of …

Background Serelaxin, recombinant human relaxin-2, is a vasoactive peptide hormone with
many biological and haemodynamic effects. In a pilot study, serelaxin was safe and well …

Objective Sodium-glucose co-transporter 2 inhibitors (SGLT2-i) are a novel drug class for
the treatment of diabetes. We aimed at describing the maximal benefits and risks associated …

Traditionally, the main indication for cardiopulmonary exercise testing (CPET) in heart failure
(HF) was for the selection of candidates to heart transplantation: CPET was mainly …

Background—Overly aggressive diuresis leading to intravascular volume depletion has
been proposed as a cause for worsening renal function during the treatment of …

Objectives: This study clarified the characteristics of intrarenal Doppler ultrasonography
(IRD) profiles and their prognostic implications in heart failure (HF). Background: IRD can …