Microbial dysbiosis tunes the immune response towards allergic disease outcomes

T Augustine, M Kumar, S Al Khodor… - Clinical Reviews in …, 2023 - Springer
The hygiene hypothesis has been popularized as an explanation for the rapid increase in
allergic disease observed over the past 50 years. Subsequent epidemiological studies have …

Multiple sclerosis and the microbiota: Progress in understanding the contribution of the gut microbiome to disease

HJ Engelenburg, PJ Lucassen… - … medicine, and public …, 2022 - academic.oup.com
Multiple sclerosis (MS), a neurological autoimmune disorder, has recently been linked to
neuro-inflammatory influences from the gut. In this review, we address the idea that …

[HTML][HTML] Focus: Chronic Disease: Reevaluating Biota Alteration: Reframing Environmental Influences on Chronic Immune Disorders and Exploring Novel Therapeutic …

W Parker, K Jirků, E Patel, L Williamson… - The Yale Journal of …, 2024 - ncbi.nlm.nih.gov
Environmental mismatches are defined as changes in the environment that induce public
health crises. Well known mismatches leading to chronic disease include the availability of …

Evolution of a Pathogenic Microbiome

PY Wong, C Yip, DA Lemberg, AS Day… - Journal of Clinical …, 2023 - mdpi.com
The process of microbiome development arguably begins before birth. Vertical transmission
of bacteria from the mother to the infant is a keystone event in microbiome development …

COVID-19 morbidity in lower versus higher income populations underscores the need to restore lost biodiversity of eukaryotic symbionts

W Parker, E Patel, K Jirků-Pomajbíková, JD Laman - Iscience, 2023 - cell.com
The avoidance of infectious disease by widespread use of 'systems hygiene', defined by
hygiene-enhancing technology such as sewage systems, water treatment facilities, and …

[HTML][HTML] Altered gut ecosystems plus the microbiota's potential for rapid evolution: a recipe for inevitable change with unknown consequences

C You, M Jirků, DL Corcoran, W Parker… - Computational and …, 2021 - Elsevier
In a single human gut, which is estimated to produce 1000-times more bacteria in a single
day than the entire human population on Earth as of 2020, the potential for evolution is vast …

Evolutionary Medicine: An Introduction

C Beeson, E Kosal - The American Biology Teacher, 2023 - online.ucpress.edu
Evolutionary medicine is a growing area of research and practice; however, it is not widely
discussed in introductory biology courses. Because of the interest in human biology, using …

[PDF][PDF] Multiple sclerosis and the microbiota

HJ Engelenburg, PJ Lucassen, JT Sarafian, W Parker… - researchgate.net
Multiple sclerosis (MS), a neurological autoimmune disorder, has recently been linked to
neuroinflammatory influences from the gut. In this review, we address the idea that …