The childhood-onset or juvenile idiopathic inflammatory myopathies (JIIMs) are a
heterogenous group of rare and serious autoimmune diseases of children and young …

Dermatomyositis (DM) is an autoimmune disorder in which clinically amyopathic DM,
characterised by hallmark cutaneous findings in the absence of clinical weakness …

Objective To evaluate the efficacy and safety of subcutaneous (SC) abatacept and standard
of care (SOC) for the treatment of idiopathic inflammatory myopathy (IIM) over 52 weeks …

Importance Cutaneous disease in dermatomyositis has no standardized treatment approach
and so presents a challenging task for patients and clinicians. Objective To study the efficacy …

Juvenile dermatomyositis (JDM) is a rare heterogeneous immune-medicated condition with
characteristic skin rashes, muscle weakness, vasculopathy, and other organ involvement …

Introduction For idiopathic inflammatory myopathies (IIM)('myositis') standard initial treatment
is high-dosed glucocorticoids, which results in relatively slow improvement of muscle …

Juvenile dermatomyositis (JDM) is one of several childhood-onset autoimmune disorders
characterized by a type I IFN response and autoantibodies. Treatment options are limited …

In the past decade, there have been six industry-sponsored phase 3 trials in adult patients
with dermatomyositis (DM), primarily focusing on improving muscle weakness. However …

特发性炎性肌病(IIM) 是一种慢性近端肌肉炎症, 并以肌无力为主要特征的全身性自身免疫性
疾病, 可累及多个系统及器官. 由于疾病活动, IIM 患者日常生活质量和工作均受到不同程度的 …

Objectives DM-related acute/subacute interstitial lung disease (A/S-ILD) remains a big
therapeutic challenge due to its insidious onset and rapid development. In the present study …