Gut microbiome and space travelers' health: state of the art and possible pro/prebiotic strategies for long-term space missions
The upcoming exploration missions will imply a much longer duration than any of the
missions flown so far. In these missions, physiological adaptation to the new environment …
missions flown so far. In these missions, physiological adaptation to the new environment …
How does spaceflight affect the acquired immune system?
The impact of spaceflight on the immune system has been investigated extensively during
spaceflight missions and in model experiments conducted on Earth. Data suggest that the …
spaceflight missions and in model experiments conducted on Earth. Data suggest that the …
Microgravity and immune cells
H Lv, H Yang, C Jiang, J Shi… - Journal of the …, 2023 - royalsocietypublishing.org
The microgravity environment experienced during spaceflight severely impaired immune
system, making astronauts vulnerable to various diseases that seriously threaten the health …
system, making astronauts vulnerable to various diseases that seriously threaten the health …
May the force be with you (or not): The immune system under microgravity
All terrestrial organisms have evolved and adapted to thrive under Earth's gravitational force.
Due to the increase of crewed space flights in recent years, it is vital to understand how the …
Due to the increase of crewed space flights in recent years, it is vital to understand how the …
Next generation of astronauts or ESA astronaut 2.0 concept and spotlight on immunity
P Jacob, C Oertlin, B Baselet, LS Westerberg… - npj …, 2023 - nature.com
Although we have sent humans into space for more than 50 years, crucial questions
regarding immune response in space conditions remain unanswered. There are many …
regarding immune response in space conditions remain unanswered. There are many …
Gravitational influence on human living systems and the evolution of species on earth
Gravity constituted the only constant environmental parameter, during the evolutionary
period of living matter on Earth. However, whether gravity has affected the evolution of …
period of living matter on Earth. However, whether gravity has affected the evolution of …
B-cell homeostasis is maintained during two months of head-down tilt bed rest with or without antioxidant supplementation
J Bonnefoy, B Baselet, D Moser, S Ghislin… - Frontiers in …, 2022 - frontiersin.org
Alterations of the immune system could seriously impair the ability to combat infections
during future long-duration space missions. However, little is known about the effects of …
during future long-duration space missions. However, little is known about the effects of …
Plasticity of the human IgM repertoire in response to long‐term spaceflight
JI Buchheim, S Ghislin, N Ouzren… - The FASEB …, 2020 - Wiley Online Library
Immune dysregulation is among the main adverse outcomes of spaceflight. Despite the
crucial role of the antibody repertoire in host protection, the effects of spaceflight on the …
crucial role of the antibody repertoire in host protection, the effects of spaceflight on the …
Mechanosensing by Gli1+ cells contributes to the orthodontic force‐induced bone remodelling
Objectives Gli1+ cells have received extensive attention in tissue homeostasis and injury
mobilization. The aim of this study was to investigate whether Gli1+ cells respond to force …
mobilization. The aim of this study was to investigate whether Gli1+ cells respond to force …
Identification of gravity-responsive proteins in the femur of spaceflight mice using a quantitative proteomic approach
K Egashira, Y Ino, Y Nakai, T Ohira, T Akiyama… - Journal of …, 2023 - Elsevier
Although the microgravity (μ-g) environment that astronauts encounter during spaceflight
can cause severe acute bone loss, the molecular mechanism of this bone loss remains …
can cause severe acute bone loss, the molecular mechanism of this bone loss remains …