Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Recent advances in isobaric labeling and applications in quantitative proteomics

MK Sivanich, TJ Gu, DN Tabang, L Li - Proteomics, 2022 - Wiley Online Library
Mass spectrometry (MS) has emerged at the forefront of quantitative proteomic techniques.
Liquid chromatography‐mass spectrometry (LC‐MS) can be used to determine abundances …

Single‐Cell Mass Spectrometry for Discovery Proteomics: Quantifying Translational Cell Heterogeneity in the 16‐Cell Frog (Xenopus) Embryo

C Lombard‐Banek, SA Moody… - Angewandte Chemie, 2016 - Wiley Online Library
We advance mass spectrometry from a cell population‐averaging tool to one capable of
quantifying the expression of diverse proteins in single embryonic cells. Our instrument …

Biomarker discovery in mass spectrometry‐based urinary proteomics

S Thomas, L Hao, WA Ricke, L Li - PROTEOMICS–Clinical …, 2016 - Wiley Online Library
Urinary proteomics has become one of the most attractive topics in disease biomarker
discovery. MS‐based proteomic analysis has advanced continuously and emerged as a …

Analytic framework for peptidomics applied to large-scale neuropeptide identification

A Secher, CD Kelstrup, KW Conde-Frieboes… - Nature …, 2016 - nature.com
Large-scale mass spectrometry-based peptidomics for drug discovery is relatively
unexplored because of challenges in peptide degradation and identification following tissue …

Mass spectrometry in plant-omics

E Gemperline, C Keller, L Li - Analytical chemistry, 2016 - ACS Publications
Plant-omics is rapidly becoming an important field of study in the scientific community due to
the urgent need to address many of the most important questions facing humanity today with …

Label-free quantification of proteins in single embryonic cells with neural fate in the cleavage-stage frog (Xenopus laevis) embryo using capillary electrophoresis …

C Lombard-Banek, S Reddy, SA Moody… - Molecular & Cellular …, 2016 - ASBMB
Quantification of protein expression in single cells promises to advance a systems-level
understanding of normal development. Using a bottom-up proteomic workflow and …

Recent advances in mass spectrometry analysis of neuropeptides

A Phetsanthad, NQ Vu, Q Yu… - Mass spectrometry …, 2023 - Wiley Online Library
Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

Tapered-tip capillary electrophoresis nano-electrospray ionization mass spectrometry for ultrasensitive proteomics: the mouse cortex

SB Choi, M Zamarbide, MC Manzini… - Journal of the American …, 2016 - ACS Publications
Ultrasensitive characterization of the proteome raises the potential to understand how
differential gene expression orchestrates cell heterogeneity in the brain. Here, we report a …

Capillary electrophoresis coupled to MALDI mass spectrometry imaging with large volume sample stacking injection for improved coverage of C. borealis …

K DeLaney, L Li - Analyst, 2020 - pubs.rsc.org
Neuropeptides are important signaling molecules responsible for a wide range of functions
within the nervous and neuroendocrine system. However, they are difficult to study due to …