Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

Breast cancer (BC) is a heterogeneous disease which has been characterised and stratified
by many platforms such as clinicopathological risk factors, genomic assays, computer …

Background The aims of this study were to characterize the metabolite profiles of triple
negative breast cancer (TNBC) and to investigate the metabolite profiles associated with …

Breast cancer accounts for the largest number of newly diagnosed cases in female cancer
patients. Although mammography is a powerful screening tool, about 20% of breast cancer …

Cancer treatment options are increasing. However, even among the same tumor histotype,
interpatient tumor heterogeneity should be considered for best therapeutic result …

Metabolic rearrangements subsequent to malignant transformation are not well
characterized in endometrial cancer. Identification of altered metabolites could facilitate …

Background Prostate cancer (PC) is a heterogenous multifocal disease ranging from
indolent to lethal states. For improved treatment-stratification, reliable approaches are …

Metabolomics represents a more recent addition to the range of omics tools, which are
increasingly used in clinical applications. By measuring the composition of small molecules …

Background Locally advanced breast cancer is a heterogeneous disease with respect to
response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to …

Detection of metabolic signature for breast cancer (BC) has the potential to improve patient
prognosis. This study identified potentially significant metabolites differentiating between …