Xanthine oxidase, a molybdo-flavoenzyme, and an isoform of xanthine dehydrogenase both
exist as xanthine oxidoreductase and are responsible for purine catabolism. Xanthine …

Xanthine oxidase (XO) is the enzyme responsible for the catabolism of purines and their
conversion into uric acid. XO is thus the target for the treatment of hyperuricemia and gout …

Carcinoma, characterized by abnormal growth of cells and tissue, is a ubiquitously leading
cause of mortality across the globe due to some carcinogenic factors. Currently, several …

Xanthine oxidase (XO) is an interesting target for the synergic treatment of several diseases.
Coumarin scaffold plays an important role in the design of efficient and potent inhibitors. In …

Xanthine oxidase (XO) has emerged as an important target for the treatment of
hyperuricemia and gout. In this study, to obtain novel nonpurine XO inhibitors, a series of 1 …

Xanthine oxidase (XO) plays a critical role in the progression of gout. We showed in a
previous study that Sanghuangporus vaninii (S. vaninii), a perennial, medicinal, and edible …

Five undescribed (four guaianolide sesquiterpenes and a benzoate ester derivative) and
seven known compounds were isolated from the aerial parts of S. orientalis L. Their …

Xanthine oxidase (XO) has been well-recognized as a key enzyme in the pathogenesis of
hyperuricemia. In this study, Chuanxiong Rhizome, a tonic food widely consumed in China …

Xanthine oxidase (XO) inhibitors are commonly used to treat gout, nephropathy, and renal
stone diseases related to hyperuricemia. However, recent research has shown that these …

Abstract A series of 5-substituted-1H-tetrazoles have been efficiently synthesized in
moderate to excellent yields (68–90%) under mild reaction conditions by combining aryl …