Highly porous and drug-loaded amorphous solid dispersion microfiber scaffolds of indomethacin prepared by melt electrowriting
Melt electrowriting (MEW) is an additive manufacturing technology enabling the production
of highly porous microfiber scaffolds, suggested in particular for use in biomedical …
of highly porous microfiber scaffolds, suggested in particular for use in biomedical …
POxload: Machine Learning Estimates Drug Loadings of Polymeric Micelles
Block copolymers, composed of poly (2-oxazoline) s and poly (2-oxazine) s, can serve as
drug delivery systems; they form micelles that carry poorly water-soluble drugs. Many recent …
drug delivery systems; they form micelles that carry poorly water-soluble drugs. Many recent …
[HTML][HTML] Amorphous solid dispersions of amphiphilic polymer excipients and indomethacin prepared by hot melt extrusion
L Keßler, R Mishra, S Hietala, M Lammens… - European Journal of …, 2025 - Elsevier
Improving the solubility of poorly water-soluble drugs is essential for enhancing
bioavailability, formulation flexibility and reducing patient-to-patient variability. The …
bioavailability, formulation flexibility and reducing patient-to-patient variability. The …
Unravel the tangle: atomistic insight into ultrahigh curcumin-loaded poly (2-oxazoline) and poly (2-oxazine)-based micelles
Amphiphilic ABA-triblock copolymers, comprised of poly (2-oxazoline) and poly (2-oxazine)
blocks, can solubilize poorly water-soluble molecules; they form micelles with exceptionally …
blocks, can solubilize poorly water-soluble molecules; they form micelles with exceptionally …
Molecular and Statistical Modeling of Polymeric Micelles
Poor solubility of novel drug candidates represents a major obstacle during formulation
development [1]. However, selecting the most suitable nanocarrier technology for a specific …
development [1]. However, selecting the most suitable nanocarrier technology for a specific …