Effect of liver metastasis on the efficacy of immune checkpoint inhibitors in cancer patients: a systemic review and meta-analysis

BW Tian, CL Han, HC Wang, LJ Yan, ZN Ding… - Clinical & Experimental …, 2023 - Springer
Liver metastasis is a frequent phenomenon in advanced tumor disease. Immune checkpoint
inhibitors (ICIs) are a new class of therapeutics that can improve the prognosis of cancer …

Immunotherapy targeting PD‑1/PD‑L1: A potential approach for the treatment of cancer bone metastases

T Hiraga - International Journal of Oncology, 2024 - spandidos-publications.com
Immune checkpoint molecules, such as programmed cell death 1 (PD‑1) and programmed
cell death ligand 1 (PD‑L1), have a critical role in regulating immune responses, including in …

p63 orchestrates serine and one carbon metabolism enzymes expression in head and neck cancer

A Cappello, G Tosetti, A Smirnov, C Ganini, X Yang… - Biology Direct, 2023 - Springer
Background Head and neck squamous cell carcinoma (HNSCC) is characterized by high
proliferation and limited differentiation. The altered expression of the p53 family members …

Serine and one-carbon metabolism sustain non-melanoma skin cancer progression

A Cappello, A Zuccotti, M Mancini, G Tosetti… - Cell Death …, 2023 - nature.com
Non-melanoma skin cancer (NMSC) is a tumor that arises from human keratinocytes,
showing abnormal control of cell proliferation and aberrant stratification. Cutaneous basal …

Genetically driven predisposition leads to an unusually genomic unstable renal cell carcinoma

M Scimeca, V Rovella, S Caporali, Y Shi, J Bischof… - Discover Oncology, 2024 - Springer
Renal cell carcinoma originates from the lining of the proximal convoluted renal tubule and
represents the most common type of kidney cancer. Risk factors and comorbidities might be …