The long-standing knowledge that Sertoli cells determine fetal testosterone production
levels is not widespread, despite being first reported over a decade ago in studies of mice …

During male fetal development, testosterone plays an essential role in the differentiation and
maturation of the male reproductive system. Deficient fetal testosterone production can result …

Leydig cells (LCs) are the major androgen-producing cells in the testis. They arise from
steroidogenic progenitors (SPs), whose origins, maintenance, and differentiation dynamics …

Spermatogenesis holds considerable promise for human-assisted reproduction and
livestock breeding based on stem cells. It occurs in seminiferous tubules within the testis …

The testis is responsible for sperm production and androgen synthesis. Abnormalities in
testis development and function lead to disorders of sex development and male infertility …

Stem Leydig cells (SLCs) play a critical role in the development and maintenance of the
adult Leydig cell (ALC) population. SLCs also are present in the adult testis. Their …

Background Testicular macrophages (TM) have long been recognized for their role in
immune response within the testicular environment. However, their involvement in steroid …

Spermatogenesis is a crucial indicator of geese reproduction performance and production.
The testis is the main organ responsible for sperm production, and the egg-laying cycle in …

Increasing rates of infertility associated with declining sperm counts and quality, as well as
increasing rates of testicular cancer are contemporary issues in the United States and …

Adrenal cortex and gonads represent the two major steroidogenic organs in mammals. Both
tissues are considered to share a common developmental origin characterized by the …