Do men die young and sick, or do women live long and healthy? By trying to explain the
sexual dimorphism in life expectancy, both biological and environmental aspects are …

Sexuality is important for most cisgender as well as transgender persons and is an essential
aspect of quality of life. For both the patient and their clinicians, managing gender dysphoria …

Context The lack of sensitive and robust analytical methods has hindered the reliable
quantification of estrogen metabolites in subjects with low concentrations. Objective To …

Androgens are potent drugs requiring prescription for valid medical indications but are
misused for invalid, unproven, or off-label reasons as well as being abused without …

This narrative review presents an overview of current knowledge on fertility and reproductive
hormone changes in aging men, the factors driving and modulating these changes, their …

Abstract In men>~ 35 years, aging is associated with perturbations in the hypothalamus-
pituitary–testicular axis and declining serum testosterone concentrations. The major …

The impact of sex hormones on anticancer immunity deserves attention due to the
importance of the immune system in cancer therapy and the recognition of sex differences in …

Background Sex hormone and preexposure prophylaxis (PrEP) drug interactions among
transgender women (TGW), transgender men (TGM), and cisgender men (CGM) are not fully …

Osteoporosis does not only affect postmenopausal women, but also ageing men. The
burden of disease is projected to increase with higher life expectancy both in females and …

Aim The age-specific population profiles in men of circulating testosterone and its two
bioactive metabolites dihydrotestosterone (DHT) and estradiol (E2) across the adult lifespan …