Regeneration is one of the great mysteries of biology. Planarians are flatworms capable of
dramatic feats of regeneration, which have been studied for over 2 centuries. Recent …

Regeneration is a heroic biological process that restores tissue architecture and function in
the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for …

Implantable meshes used in tension‐free repair operations facilitate treatment of internal soft‐
tissue defects. However, clinical meshes fail to achieve anti‐deformation, anti‐adhesion …

INTRODUCTION Understanding the differentiation of stem cells into the vast amount of cell
types that form the human body is a central problem of basic and medical science. The …

INTRODUCTION The complete sequence of animal genomes has had a transformative
impact on biological research. Whereas the genome sequence of an organism contains the …

Comparing single-cell transcriptomic atlases from diverse organisms can elucidate the
origins of cellular diversity and assist the annotation of new cell atlases. Yet, comparison …

Injury induces systemic responses, but their functions remain elusive. Mechanisms that can
rapidly synchronize wound responses through long distances are also mostly unknown …

Flatworms (Platyhelminthes) are a basally branching phylum that harbours a wealth of
fascinating biology, including planarians with their astonishing regenerative abilities and the …

For successful regeneration, the identity of the missing tissue must be specified according to
the pre-existing tissue. Planarians are ideal for the study of the mechanisms underlying this …

Planarian whole-body regeneration is enabled by stem cells called neoblasts. At least some
neoblasts are individually pluripotent. Neoblasts are also heterogeneous, with …