Light-scattering methods for tissue diagnosis

ZA Steelman, DS Ho, KK Chu, A Wax - Optica, 2019 - opg.optica.org
Light scattering has become a common biomedical research tool, enabling diagnostic
sensitivity to myriad tissue alterations associated with disease. Light–tissue interactions are …

Comparison of imaging fiber bundles for coherence-domain imaging

ZA Steelman, S Kim, ET Jelly, M Crose, KK Chu… - Applied …, 2018 - opg.optica.org
Use of imaging fiber bundles for coherence-domain imaging has remained limited to date. In
this work, we provide characterization of commercially available imaging bundles for …

Response to Comment on “Is the nuclear refractive index lower than cytoplasm? Validation of phase measurements and implications for light scattering technologies”

ZA Steelman, WJ Eldridge, A Wax - Journal of biophotonics, 2018 - Wiley Online Library
Recently, Maxim A. Yurkin commented on our paper “Is the nuclear refractive index lower
than cytoplasm? Validation of phase measurements and implications for light scattering …

Angular range, sampling and noise considerations for inverse light scattering analysis of nuclear morphology

H Zhang, ZA Steelman, DS Ho, KK Chu… - Journal of …, 2019 - Wiley Online Library
In recent years, significant work has been devoted to the use of angle‐resolved elastic
scattering for the extraction of nuclear morphology in tissue. By treating the nucleus as a Mie …

Prospective detection of cervical dysplasia with scanning angle-resolved low coherence interferometry

WY Kendall, D Ho, K Chu, M Zinaman… - Biomedical Optics …, 2020 - opg.optica.org
We present a prospective clinical study using angle-resolved low-coherence interferometry
(a/LCI) to detect cervical dysplasia via depth resolved nuclear morphology measurements …

Spatial scanning of a sample with two-dimensional angle-resolved low-coherence interferometry for analysis of anisotropic scatterers

G Song, ZA Steelman, W Kendall, HS Park… - Biomedical Optics …, 2020 - opg.optica.org
Angle-resolved low-coherence interferometry (a/LCI) measures depth-resolved angular
scattering for cell nuclear morphology analysis. 2D a/LCI, developed to collect across two …

[HTML][HTML] Reconstruction of angle-resolved backscattering through a multimode fiber for cell nuclei and particle size determination

H Zhang, ZA Steelman, S Ceballos, KK Chu, A Wax - APL photonics, 2020 - pubs.aip.org
We demonstrate the reconstruction of angle-resolved optical backscattering after
transmission through a multimode fiber. Angle-resolved backscattering is an important tool …

Advanced imaging for Barrett's esophagus and early neoplasia: surface and subsurface imaging for diagnosis and management

M Mkarimi, H Mashimo - Current Gastroenterology Reports, 2018 - Springer
Abstract Purpose of Review Esophageal adenocarcinoma bears one of the fastest rising
incidence of any cancers and generally arises in the setting of gastroesophageal reflux and …

Development of optical technologies for comprehensive screening of cervical epithelial health

DS Ho - 2019 - search.proquest.com
Cervical cancer is one of the most common gynecologic malignancies with significant
morbidity and mortality globally. However, most pre-cancers are easily treatable such that …

Novel Low Coherence Interferometric Tools for Early Detection of Cancer

WY Kendall - 2023 - search.proquest.com
Cancer encompasses many diseases affecting all parts of the body, is characterized by
rapid, abnormal cell growth, and is one of the most common causes of death worldwide …