Understanding molecular signaling cascades in neural disease using multi-resolution models

NA Viswan, US Bhalla - Current opinion in neurobiology, 2023 - Elsevier
If the genome defines the program for the operations of a cell, signaling networks execute it.
These cascades of chemical, cell-biological, structural, and trafficking events span …

[HTML][HTML] Combining hypothesis-and data-driven neuroscience modeling in FAIR workflows

O Eriksson, US Bhalla, KT Blackwell, SM Crook… - Elife, 2022 - elifesciences.org
Modeling in neuroscience occurs at the intersection of different points of view and
approaches. Typically, hypothesis-driven modeling brings a question into focus so that a …

Seismic Stability Assessment of Civil Building Projects Based on BIM Technology

R Zhao - International Conference on Innovative Computing, 2023 - Springer
Abstract Building Information Modelling (BIM) technology is in a rapid stage of development
in China. BIM technology is the use of computer information means to simulate information …

The Important Role of Systems Biology in Neuroscience and Neurology and Its Associated Diseases

M Haripriyaa, K Suthindhiran - Systems Biology Approaches: Prevention …, 2024 - Springer
Neurodegenerative diseases are a huge global health concern in the Western world due to
our ageing population and other factors. Research into these illnesses is therefore essential …

Sensitivity analysis of biophysically-detailed tripartite synapse model

I Seppälä, T Manninen, ML Linne - IFAC-PapersOnLine, 2022 - Elsevier
Now that mathematical models are becoming larger and biophysically more detailed,
understanding how each variable, parameter, and equation affects the outcome of the model …