Obsessive-compulsive disorder (OCD) is as serious devastating anxiety disorder. Selective serotonin reuptake inhibitors (SSRIs) are largely used for the treatment of this mental …
Obsessive-compulsive disorder (OCD) is a disabling mental condition that poses recurring bothersome intrusive thoughts, obsessions, and compulsions. Considering the positive …
PS Chong, CH Poon, ML Fung, L Guan… - Acta histochemica, 2019 - Elsevier
Neuronal NOS (nNOS) accounts for most of the NO production in the nervous system that modulates synaptic transmission and neuroplasticity. Although previous studies have …
Background Inflammation and oxidative stress are recognized as important contributors to Parkinson's disease pathogenesis. As such, genetic variability in these pathways could have …
CL Tosta, GP Silote, MP Fracalossi, AG Sartim… - …, 2019 - Elsevier
Previous clinical and pre-clinical studies suggest the involvement of ventromedial orbitofrontal cortex (vmOFC) and glutamatergic neurotransmission in obsessive-compulsive …
Background The most common psychiatric complications due to dopaminergic treatment in Parkinson's disease are visual hallucinations and impulse control disorders. Their …
Y Özkan, H Kandemir, ŞY Sapmaz, F Taneli - Journal of Obsessive …, 2021 - Elsevier
The biological mechanisms underlying obsessive–compulsive disorder (OCD) are not sufficiently elucidated. Chronic inflammation and oxidative stress were shown to increase …
Background This study aimed to evaluate whether VNTR variants in the Endothelial Nitric Oxide Synthase (eNOS) and the XRCC4 gene play any role in nicotine dependence (ND) …
R Rovný, M Marko, G Minarik… - Physiological Research, 2021 - ncbi.nlm.nih.gov
The neurotransmitter serotonin has been critically implicated in the pathogenesis of several mental disorders. The serotonin transporter (5-HTT) is a key regulator of serotonergic …