Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain
and body. The apparent simplicity of breathing belies a complex neural control system, the …

Sudden unexpected death in epilepsy (SUDEP) can affect individuals of any age, but is most
common in younger adults (aged 20–45 years). Generalised tonic-clonic seizures are the …

Objective New devices are needed for monitoring seizures, especially those associated with
sudden unexpected death in epilepsy (SUDEP). They must be unobtrusive and automated …

Olfactory stimulus acquisition is perfectly synchronized with inhalation, which tunes neuronal
ensembles for incoming information. Because olfaction is an ancient sensory system that …

Objective To characterize peri-ictal apnea and postictal asystole in generalized convulsive
seizures (GCS) of intractable epilepsy. Methods This was a prospective, multicenter epilepsy …

The amygdala is a key structure mediating emotional processing. Few studies have used
direct electrical stimulation of the amygdala in humans to examine stimulation-elicited …

Objective The aim of this study was to investigate periictal central apnea as a seizure
semiological feature, its localizing value, and possible relationship with sudden unexpected …

Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to
nerve agents can cause rapid death. In this review, we summarize the history of nerve agent …

The key driver of breathing rhythm is the preBötzinger Complex (preBötC) whose activity is
modulated by various functional inputs, eg, volitional, physiological, and emotional. While …

Dravet syndrome (DS) is a severe childhood-onset epilepsy commonly due to mutations of
the sodium channel gene SCN1A. Patients with DS have a high risk of sudden unexplained …