Computational investigation of a series of small molecules as potential compounds for lysyl hydroxylase-2 (LH2) inhibition

Y Maghsoud, EA Vázquez-Montelongo… - Journal of chemical …, 2023 - ACS Publications
The catalytic function of lysyl hydroxylase-2 (LH2), a member of the Fe (II)/αKG-dependent
oxygenase superfamily, is to catalyze the hydroxylation of lysine to hydroxylysine in …

Molecular Structure and Enzymatic Mechanism of the Human Collagen Hydroxylysine Galactosyltransferase GLT25D1/COLGALT1

M De Marco, SR Rai, L Scietti, D Mattoteia, S Liberi… - bioRxiv, 2024 - biorxiv.org
During biosynthesis, collagen lysine residues undergo extensive post-translational
modifications essential for the stability and functions of collagen supramolecular assemblies …

[PDF][PDF] Microarray Analysis Reveals Altered Genes Involved in Apoptosis, Inflammation and Bone Metabolism in Knee Osteoarthritis

V Chandra, MT Ashraf, P Yadav, V Raghuvanshi - researchgate.net
Background: Osteoarthritis (OA) is a common rheumatic disorder that affects multiple joint
tissues and has complex genetic and environmental etiologies. This study explores the …