Fibrillin is a large evolutionarily ancient extracellular glycoprotein that assembles to form
beaded microfibrils which are essential components of most extracellular matrices. Fibrillin …

Purpose: The purpose of the experiments described here was to determine the effects of
lipoic acid (LA)-dependent disulfide reduction on mouse lens elasticity, to synthesize the …

A thorough understanding of normal ophthalmic anatomy is an integral part of the
foundational knowledge of a veterinary ophthalmologist. It is important to be able to …

Purpose.: Here, we examined the development, composition, and structural organization of
the ciliary zonule of the mouse. Fibrillin 1, a large glycoprotein enriched in force-bearing …

Purpose.: Fibrillins are the major constituent of tissue microfibrils, which form the ocular
zonule. In Marfan syndrome (MFS), FBN1 mutations lead to ectopia lentis. The goal of this …

Fibrillin microfibrils are evolutionarily ancient, structurally complex extracellular polymers
found in mammalian elastic tissues where they endow elastic properties, sequester growth …

Purpose: This study aimed to quantify the three-dimensional micromorphology of the surface
of the human lens capsule as a function of age. Methods: Imaging experiments were …

Oxytalan fibers are distributed in the eye and periodontal ligaments (PDL). The ciliary
zonule, known as Zinn's zonule, in the eye is composed of oxytalan fibers, which are …

PURPOSE: To explore the relationship between the change in intraocular lens (IOL) position
and capsular bend after cataract surgery. METHODS: Patients underwent …

We report analysis of the ocular lens phenotype of the recessive, larval lethal zebrafish
mutant, lama1a69/a69. Previous work revealed that this mutant has a shortened body axis …