Besides damaging the brain, stroke causes systemic changes, including to the
gastrointestinal system. A growing body of evidence supports the role of the gut and its …

Stroke remains one of the main causes of mortality and morbidity worldwide. Immediately
after stroke, a neuroinflammatory process starts in the brain, triggering a systemic …

Background: Stroke-associated pneumonia (SAP) has been implicated in the morbidity,
mortality and increased medical cost after acute ischemic stroke. The annual cost of SAP …

Infections are a leading cause of morbidity and mortality in patients with acute CNS injury. It
has recently become clear that CNS injury significantly increases susceptibility to infection …

Systemic immunosuppression has been associated with stroke for many years, but the
underlying mechanisms are poorly understood. In this study, we demonstrated that stroke …

The immune response to acute cerebral ischemia is a major contributor to stroke
pathobiology. The inflammatory response is characterized by the participation of brain …

Stroke affects the normally well-balanced interplay of the 2 supersystems: the nervous and
the immune system. Recent research elucidated some of the involved signals and …

The relation between acute ischaemic stroke and infection is complex. Infection appears to
be an important trigger that precedes up to a third of ischaemic strokes and can bring about …

Background and Purpose—The selection of appropriate neurological scores and tests is
crucial for the evaluation of stroke consequences. The validity and reliability of neurological …

Background and Purpose—Infection after experimental focal ischemia may result from brain-
induced immunodepression, but it is unsettled whether a similar syndrome occurs in human …