An overview of frailty in kidney transplantation: measurement, management and future considerations

MN Harhay, MK Rao, KJ Woodside… - Nephrology Dialysis …, 2020 - academic.oup.com
The construct of frailty was first developed in gerontology to help identify older adults with
increased vulnerability when confronted with a health stressor. This article is a review of …

Frailty assessment as part of transplant listing: yes, no or maybe?

MA McAdams-DeMarco, AK Thind… - Clinical Kidney …, 2023 - academic.oup.com
Frailty, characterized by a decreased physiological reserve and an increased vulnerability to
stressors, is common among kidney transplant (KT) candidates and recipients. In this review …

Frailty prevalence in younger end-stage kidney disease patients undergoing dialysis and transplantation

NM Chu, X Chen, SP Norman, J Fitzpatrick… - American journal of …, 2020 - karger.com
Background: Frailty, originally characterized in community-dwelling older adults, is
increasingly being studied and implemented for adult patients with end-stage kidney …

Development and validation of an abridged physical frailty phenotype for clinical use: A cohort study among kidney transplant candidates

X Chen, NM Chu, V Thompson, EE Quint… - The Journals of …, 2024 - academic.oup.com
Background Frailty is associated with poor outcomes in surgical patients including kidney
transplant (KT) recipients. Transplant centers that measure frailty have better pre-and …

Transplant centers that assess frailty as part of clinical practice have better outcomes

X Chen, Y Liu, V Thompson, NM Chu, EA King… - BMC geriatrics, 2022 - Springer
Background Frailty predicts adverse post-kidney transplant (KT) outcomes, yet the impact of
frailty assessment on center-level outcomes remains unclear. We sought to test whether …

Defining the ethical considerations surrounding kidney transplantation for frail and cognitively impaired patients: a Delphi study of geriatric transplant experts

P Shrestha, SE Van Pilsum Rasmussen, EA King… - BMC geriatrics, 2022 - Springer
Background Among adult kidney transplant (KT) candidates, 21% are frail and 55% have
cognitive impairment, increasing the risk of pre-and post-KT mortality. Centers often assess …

[HTML][HTML] Kidney recipients with allograft failure, transition of kidney care (KRAFT): a survey of contemporary practices of transplant providers

T Alhamad, M Lubetzky, KL Lentine, E Edusei… - American Journal of …, 2021 - Elsevier
Kidney allograft failure and return to dialysis carry a high risk of morbidity. A practice survey
was developed by the AST Kidney Pancreas Community of Practice workgroup and …

[HTML][HTML] Revision of frailty assessment in kidney transplant recipients: replacing unintentional weight loss with CT-assessed sarcopenia in the physical frailty …

X Chen, O Shafaat, Y Liu, EA King, CR Weiss… - American Journal of …, 2022 - Elsevier
Kidney transplantation (KT) experts did not support the use of subjective unintentional
weight loss to measure shrinking in the physical frailty phenotype (PFP); a clinically feasible …

Immunosuppression regimen use and outcomes in older and younger adult kidney transplant recipients: a national registry analysis

KL Lentine, W Cheungpasitporn, H Xiao… - …, 2021 - journals.lww.com
Background. Although the population of older transplant recipients has increased
dramatically, there are limited data describing the impact of immunosuppression regimen …

Development and validation of an inflammatory-frailty index for kidney transplantation

CE Haugen, A Gross, NM Chu… - The Journals of …, 2021 - academic.oup.com
Background Physical frailty phenotype is characterized by decreased physiologic reserve to
stressors and associated with poor outcomes, such as delirium and mortality, that may result …