Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas

JL Boxerman, CC Quarles, LS Hu, BJ Erickson… - Neuro …, 2020 - academic.oup.com
Despite the widespread clinical use of dynamic susceptibility contrast (DSC) MRI, DSC-MRI
methodology has not been standardized, hindering its utilization for response assessment in …

High-grade glioma treatment response monitoring biomarkers: a position statement on the evidence supporting the use of advanced MRI techniques in the clinic, and …

OM Henriksen, M del Mar Álvarez-Torres… - Frontiers in …, 2022 - frontiersin.org
Objective Summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods …

Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures

LS Hu, F D'Angelo, TM Weiskittel, FP Caruso… - Nature …, 2023 - nature.com
Sampling restrictions have hindered the comprehensive study of invasive non-enhancing
(NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present …

Imaging vascular and hemodynamic features of the brain using dynamic susceptibility contrast and dynamic contrast enhanced MRI

CC Quarles, LC Bell, AM Stokes - Neuroimage, 2019 - Elsevier
In the context of neurologic disorders, dynamic susceptibility contrast (DSC) and dynamic
contrast enhanced (DCE) MRI provide valuable insights into cerebral vascular function …

Moving toward a consensus DSC-MRI protocol: validation of a low–flip angle single-dose option as a reference standard for brain tumors

KM Schmainda, MA Prah, LS Hu… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: DSC-MR imaging using preload, intermediate (60°) flip
angle and postprocessing leakage correction has gained traction as a standard …

[HTML][HTML] Variability in quantitative DCE-MRI: sources and solutions

H Kim - Journal of nature and science, 2018 - ncbi.nlm.nih.gov
DCE-MRI has been extensively used for diagnosis, prognosis and therapy monitoring of
various diseases including cancer. However, it has been reported that the perfusion …

Multisite concordance of DSC-MRI analysis for brain tumors: results of a national cancer institute quantitative imaging network collaborative project

KM Schmainda, MA Prah, SD Rand… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Standard assessment criteria for brain tumors that only
include anatomic imaging continue to be insufficient. While numerous studies have …

In silico simulation: a key enabling technology for next-generation intelligent surgical systems

BD Killeen, SM Cho, M Armand… - Progress in …, 2023 - iopscience.iop.org
To mitigate the challenges of operating through narrow incisions under image guidance,
there is a desire to develop intelligent systems that assist decision making and spatial …

Evaluation of single bolus, dual-echo dynamic susceptibility contrast MRI protocols in brain tumor patients

AM Stokes, M Bergamino, L Alhilali… - Journal of Cerebral …, 2021 - journals.sagepub.com
Relative cerebral blood volume (rCBV) obtained from dynamic susceptibility contrast (DSC)
MRI is adversely impacted by contrast agent leakage in brain tumors. Using simulations, we …

Optimization of acquisition and analysis methods for clinical dynamic susceptibility contrast MRI using a population-based digital reference object

NB Semmineh, LC Bell, AM Stokes… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The accuracy of DSC-MR imaging CBV maps in
glioblastoma depends on acquisition and analysis protocols. Multisite protocol …