Despite the substantial contribution of disruptions in GABAergic inhibitory neurotransmission
to the etiology of psychiatric, neurodevelopmental, and neurodegenerative disorders …

Nitropyrene (1-NP), a typical nitro-polycyclic aromatic hydrocarbon, is a developmental
toxicant. This study was to evaluate gestational 1-NP-induced anxiety-like behavior in male …

Background Dendritic spines are the sites of excitatory synapses on pyramidal neurons, and
their development is crucial for neural circuits and brain functions. The spine shape, size, or …

Post-traumatic stress disorder (PTSD) often arises after exposure to traumatic events and is
characterized by dysregulated fear responses. Although the associations of erb-b2 receptor …

Anxiety disorder is one of the most common mental disorders worldwide, affecting nearly
30% of adults. However, its underlying molecular mechanisms are still unclear. Here we …

Schizophrenia is a neurodevelopmental disorder with dendrite and dendritic spine
dysfunction. Dysbindin-1, a protein decreased in the brains of schizophrenia patients, is …

Synapse formation in the mammalian brain is a complex and dynamic process requiring
coordinated function of dozens of molecular families such as cell adhesion molecules …

Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer's disease
(AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the …

The activation of members of the Epidermal Growth Factor Receptor (EGFR) family
(including ErbB) triggers pathways that have significant effects on cellular processes and …

Motivation-driven mating is a basic affair for the maintenance of species. However, the
underlying molecular mechanisms that control mating motivation are not fully understood …