[HTML][HTML] UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer

FR de Gruijl, HJ van Kranen, LHF Mullenders - Journal of Photochemistry …, 2001 - Elsevier
Repair of UV induced DNA damage is of key importance to UV-induced skin carcinogenesis.
Specific signal transduction pathways that regulate cell cycling, differentiation and apoptosis …

Cellular and sub-cellular responses to UVA in relation to carcinogenesis

AJ Ridley, JR Whiteside, TJ McMillan… - International journal of …, 2009 - Taylor & Francis
Purpose: UVA radiation (315–400 nm) contributes to skin aging and carcinogenesis. The
aim of this review is to consider the mechanisms that underlie UVA-induced cellular …

Induction of bystander effects by UVA, UVB, and UVC radiation in human fibroblasts and the implication of reactive oxygen species

M Widel, A Krzywon, K Gajda, M Skonieczna… - Free Radical Biology …, 2014 - Elsevier
Radiation-induced bystander effects are various types of responses displayed by
nonirradiated cells induced by signals transmitted from neighboring irradiated cells. This …

Current and future trends in molecular biomarkers for diagnostic, prognostic, and predictive purposes in non-melanoma skin cancer

TK Nikolouzakis, L Falzone, K Lasithiotakis… - Journal of Clinical …, 2020 - mdpi.com
Skin cancer represents the most common type of cancer among Caucasians and presents in
two main forms: melanoma and non-melanoma skin cancer (NMSC). NMSC is an umbrella …

Cellular effects of long wavelength UV light (UVA) in mammalian cells

TJ McMillan, E Leatherman, A Ridley… - Journal of Pharmacy …, 2008 - Wiley Online Library
UVA should receive significant consideration as a human health risk as it is a large
proportion of the solar spectrum that reaches the earth's surface and because of its ability to …

Health effects from stratospheric ozone depletion and interactions with climate change

FR De Gruijl, J Longstreth, M Norval… - Photochemical & …, 2003 - pubs.rsc.org
The potential health effects of elevated levels of ambient UV-B radiation are diverse, and it is
difficult to quantify the risks, especially as they are likely to be considerably modified by …

UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes

K Wischermann, S Popp, S Moshir… - Oncogene, 2008 - nature.com
The role of UVA-radiation—the major fraction in sunlight—in human skin carcinogenesis is
still elusive. We here report that different UVA exposure regime (4× 5 J/cm 2 per week or 1× …

[HTML][HTML] Genotoxicity of visible light (400–800 nm) and photoprotection assessment of ectoin, L-ergothioneine and mannitol and four sunscreens

C Botta, C Di Giorgio, AS Sabatier, M De Méo - Journal of Photochemistry …, 2008 - Elsevier
This study was designed to determine the genotoxic effects of visible (400–800nm) and
ultraviolet A (UVA)/visible (315–800nm) lights on human keratinocytes and CHO cells. The …

Low concentrations of formaldehyde induce DNA damage and delay DNA repair after UV irradiation in human skin cells

G Emri, D Schaefer, B Held, C Herbst… - Experimental …, 2004 - Wiley Online Library
Long‐term occupational exposure to formaldehyde (FA) increases the risk for
nasopharyngeal squamous cell carcinoma. As the skin is also in contact with FA by …

[HTML][HTML] Protective effect of Arthrospira platensis extracts against ultraviolet B-induced cellular senescence through inhibition of DNA damage and matrix …

JJ Lee, KB Kim, J Heo, DH Cho, HS Kim… - … of Photochemistry and …, 2017 - Elsevier
Ultraviolet (UV) light exposure causes skin photoaging, which is known to be preventable
and controllable by application of UV-protective agents. In this study, we demonstrated, for …