Many medical devices such as cardiopulmonary bypass systems, mechanical heart valves,
or ventricular assist devices are intended to come into contact with blood flow during use. In …

Despite growing use of mechanical circulatory support, limitations remain related to
hemocompatibility. Here, we performed a head-to-head comparison of the …

Introduction In vitro hemolysis testing is an essential method for assessing the hemolytic
potential of blood pumps, but has poor reproducibility. Further investigations are needed to …

Purpose: Blood damage has been associated with patients under temporary continuous-
flow mechanical circulatory support. To evaluate the side effects caused by transit blood …

Background Membranes based on triply periodic minimal surfaces (TPMS) have proven a
superior gas transfer compared to the contemporary hollow fiber membrane (HFM) design in …

Thrombosis is the main reason for the failure of ventricular assist devices (VADs). It has
been acknowledged that the platelet activation induced by the nonphysiological blood flow …

Management of heart and respiratory failure has improved in recent years in parallel with
advancements in pharmacological interventions and organ transplant. The advent of …

Background: This study was conducted to confirm the reliability of an in vitro mechanically
induced hemolysis test (ISO 10993-4: 2017), which is essential for ensuring the safety of …

In vitro thrombogenicity tests for rotary blood pumps (RBPs) could benefit from assessing
coagulation kinematics, as RBP design improves. In this feasibility study, we investigated if …

Despite improved hemocompatibility of left-ventricular assist devices (LVADs), assessment
of blood damage remains mandatory in preclinical testing as standardized by ASTM-F1841 …