Chemical reversible crosslinking enables measurement of RNA 3D distances and alternative conformations in cells

R Van Damme, K Li, M Zhang, J Bai, WH Lee… - Nature …, 2022 - nature.com
Abstract Three-dimensional (3D) structures dictate the functions of RNA molecules in a wide
variety of biological processes. However, direct determination of RNA 3D structures in vivo is …

Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases

M Zhang, K Li, J Bai, WA Velema, C Yu… - Nature …, 2021 - nature.com
Direct determination of RNA structures and interactions in living cells is critical for
understanding their functions in normal physiology and disease states. Here, we present …