[HTML][HTML] Targeted therapy approaches for epithelial-mesenchymal transition in triple negative breast cancer

M Haque, RK Shyanti, MK Mishra - Frontiers in Oncology, 2024 - pmc.ncbi.nlm.nih.gov
Triple-negative breast cancer (TNBC) is distinguished by negative expression of estrogen
receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 …

Transcriptome analysis of diffuse large b-cell lymphoma cells inducibly expressing MyD88 L265P mutation identifies upregulated CD44, LGALS3, NFKBIZ, and BATF …

M Turi, A Anilkumar Sithara, L Hofmanová… - International Journal of …, 2023 - mdpi.com
During innate immune responses, myeloid differentiation primary response 88 (MyD88)
functions as a critical signaling adaptor protein integrating stimuli from toll-like receptors …

[HTML][HTML] Fat Mass-and Obesity-Associated Protein (FTO) Promotes the Proliferation of Goat Skeletal Muscle Satellite Cells by Stabilizing DAG1 mRNA in an IGF2BP1 …

J Yao, L Xu, Z Zhao, D Dai, S Zhan, J Cao… - International Journal of …, 2024 - mdpi.com
Skeletal muscle development is spotlighted in mammals since it closely relates to animal
health and economic benefits to the breeding industry. Researchers have successfully …

The underlying mechanisms of arenaviral entry through matriglycan

M Katz, R Diskin - Frontiers in Molecular Biosciences, 2024 - frontiersin.org
Matriglycan, a recently characterized linear polysaccharide, is composed of alternating
xylose and glucuronic acid subunits bound to the ubiquitously expressed protein α …

Silencing GMPPB Inhibits the Proliferation and Invasion of GBM via Hippo/MMP3 Pathways

ZL Huang, AS Abdallah, GX Shen, M Suarez… - International journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is a highly aggressive malignancy and represents the most
common brain tumor in adults. To better understand its biology for new and effective …

Glycosyltransferase-related prognostic and diagnostic biomarkers of uterine corpus endometrial carcinoma

J Wu, X Zhou, J Ren, Z Zhang, H Ju, X Diao… - Computers in Biology …, 2023 - Elsevier
Uterine corpus endometrial carcinoma (UCEC) has a strong ability of invasion and
metastasis, high recurrence rate, and poor survival. Glycosyltransferases are one of the most …

MALDI imaging combined with two-photon microscopy reveals local differences in the heterogeneity of colorectal cancer

A Bharti, K Ajinkya, MM Andrea, RG Fernanda… - npj Imaging, 2024 - nature.com
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide,
accentuated by its heterogeneity and complex tumour microenvironment (TME). The role of …

Neurexin facilitates glycosylation of Dystroglycan to sustain muscle architecture and function in Drosophila

Y Zhao, J Geng, Z Meng, Y Sun, M Ou, L Xu… - Communications …, 2024 - nature.com
Neurexin, a molecule associated with autism spectrum disorders, is thought to function
mainly in neurons. Recently, it was reported that Neurexin is also present in muscle, but the …

Suppression of dystroglycan function accompanies pancreatic acinar‐to‐ductal metaplasia and favours dysplasia development

G Huang, L Ternes, C Lanciault… - The Journal of …, 2024 - Wiley Online Library
The basement membrane (BM) is among the predominant microenvironmental factors of
normal epithelia and of precancerous epithelial lesions. Evidence suggests that the BM …

Identification and validation of a glycosyltransferase gene signature as a novel prognostic model for lung adenocarcinoma

J Zhou, K Zhang, T Yang, A Li, M Li, X Peng, M Chen - Heliyon, 2024 - cell.com
Background The role of glycosyltransferase (GT) genes in lung adenocarcinoma (LUAD)
needs further elucidation. Thus, our study aims to identify the prognostic gene signature of …