Charged particle therapy—optimization, challenges and future directions

JS Loeffler, M Durante - Nature reviews Clinical oncology, 2013 - nature.com
The use of charged particle therapy to control tumours non-invasively offers advantages
over conventional radiotherapy. Protons and heavy ions deposit energy far more selectively …

[HTML][HTML] Consensus guidelines for implementing pencil-beam scanning proton therapy for thoracic malignancies on behalf of the PTCOG thoracic and lymphoma …

JY Chang, X Zhang, A Knopf, H Li, S Mori… - International Journal of …, 2017 - Elsevier
Pencil-beam scanning (PBS) proton therapy (PT), particularly intensity modulated PT,
represents the latest advanced PT technology for treating cancers, including thoracic …

Motion in radiotherapy: particle therapy

C Bert, M Durante - Physics in Medicine & Biology, 2011 - iopscience.iop.org
Charged particle beam radiotherapy requires dedicated measures to compensate for the
dosimetric influence of inter-and intra-fractional target motion. Independent of the delivery …

Particle therapy in Europe

C Grau, M Durante, D Georg, JA Langendijk… - Molecular …, 2020 - Wiley Online Library
Particle therapy using protons or heavier ions is currently the most advanced form of
radiotherapy and offers new opportunities for improving cancer care and research. Ions …

The status of CNAO

S Rossi - The European Physical Journal Plus, 2011 - Springer
The CNAO (Italian acronym that stands for National Centre for Oncological Hadrontherapy)
has been realised in Pavia, Italy. It is a clinical facility created and financed by the Italian …

[HTML][HTML] A survey of practice patterns for real-time intrafractional motion-management in particle therapy

Y Zhang, P Trnkova, T Toshito, B Heijmen… - Physics and imaging in …, 2023 - Elsevier
Background and purpose Organ motion compromises accurate particle therapy delivery.
This study reports on the practice patterns for real-time intrafractional motion-management in …

Empowering intensity modulated proton therapy through physics and technology: an overview

R Mohan, IJ Das, CC Ling - International Journal of Radiation Oncology …, 2017 - Elsevier
Considering the clinical potential of protons attributable to their physical characteristics,
interest in proton therapy has increased greatly in this century, as has the number of proton …

Management of motion and anatomical variations in charged particle therapy: past, present, and into the future

JM Pakela, A Knopf, L Dong, A Rucinski… - Frontiers in …, 2022 - frontiersin.org
The major aim of radiation therapy is to provide curative or palliative treatment to cancerous
malignancies while minimizing damage to healthy tissues. Charged particle radiotherapy …

[HTML][HTML] Charged particles in radiotherapy: a 5-year update of a systematic review

D De Ruysscher, MM Lodge, B Jones, M Brada… - Radiotherapy and …, 2012 - Elsevier
Although proton therapy has been used for many decades because of their superior dose
distribution over photons and reduced integral dose, their clinical implementation is still …

AAPM Task Group Report 290: Respiratory motion management for particle therapy

H Li, L Dong, C Bert, J Chang, S Flampouri… - Medical …, 2022 - Wiley Online Library
Dose uncertainty induced by respiratory motion remains a major concern for treating
thoracic and abdominal lesions using particle beams. This Task Group report reviews the …