Macromolecular proton fraction (MPF) is a quantitative MRI parameter describing the
magnetization transfer (MT) effect and defined as a relative amount of protons bound to …

Background Brain imaging studies have thoroughly investigated brain gray matter
abnormalities to assess pathophysiological mechanisms underlying psychiatric illnesses …

Demyelination is observed in both healthy aging and age-related neurodegenerative
disorders. While the significance of myelin within the cortex is well acknowledged, studies …

Although gray matter (GM) abnormalities are present from the early stages of psychosis,
subtle/miniscule changes may not be detected by conventional volumetry. Texture analysis …

Whereas meta-analytical data highlight abnormal frontocortical macrostructure
(thickness/surface area/volume) in Major Depressive Disorder (MDD), the underlying …

Age-related changes of intracortical myelin in bipolar disorder (BD) have been observed to
deviate from the quadratic age curve observed in healthy controls (HC), but it is unclear if …

Background Magnetization transfer saturation (MTsat) imaging was developed to reduce T1
dependence and improve specificity to myelin, compared to the widely used MT ratio (MTR) …

Abstract Background and Hypothesis Microvascular and inflammatory mechanisms have
been hypothesized to be involved in the pathophysiology of psychotic spectrum disorders …

Transitory states of the brain, sometimes linked to particular mental disorders, can be
identified by conducting a dynamic analysis of connectivity in functional magnetic resonance …

At the moment, the study of the association of different brain areas with schizophrenia is a
thriving field of research. Although the precise mechanisms underlying the development of …