The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

Chromogranin A (CgA) is a member of the granins, a family of acidic proteins found in
abundance in (neuro) endocrine cells (eg, in chromaffin cells) and in some tumors. Like …

Hypertension is associated with inflammation and excessive production of catecholamines.
Hypertensive patients have reduced plasma levels of CST (catestatin)—a bioactive …

Importance of the field: A worldwide epidemic of chronic kidney disease (CKD) exists;
hypertensive nephropathy is second only to diabetes as a leading cause of progressive …

Hypertension is a common hereditary syndrome with unclear pathogenesis. Chromogranin
A (Chga), which catalyzes formation and cargo storage of regulated secretory granules in …

Objective Neuropeptide Y affects several physiological functions, notably appetite
regulation. We analysed the association between four single nucleotide polymorphisms …

Aims Aging is associated with the development of insulin resistance and hypertension which
may stem from inflammation induced by accumulation of toxic bacterial DNA crossing the gut …

Background—Oxidative stress, an excessive production of reactive oxygen species (ROS)
outstripping antioxidant defense mechanisms, occurs in cardiovascular pathologies …

Aim Defects in hepatic glycogen synthesis contribute to post‐prandial hyperglycaemia in
type 2 diabetic patients. Chromogranin A (CgA) peptide Catestatin (CST: hCgA352‐372) …

Processes underlying the formation of dense core secretory granules (DCGs) of
neuroendocrine cells are poorly understood. Here, we present evidence that DCG …