Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

K Oliphant, E Allen-Vercoe - Microbiome, 2019 - Springer
The human gut microbiome is a critical component of digestion, breaking down complex
carbohydrates, proteins, and to a lesser extent fats that reach the lower gastrointestinal tract …

Microbial fermentation of dietary protein: an important factor in diet–microbe–host interaction

NE Diether, BP Willing - Microorganisms, 2019 - mdpi.com
Protein fermentation by gut microbiota contributes significantly to the metabolite pool in the
large intestine and may contribute to host amino acid balance. However, we have a limited …

Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial

Y Wan, F Wang, J Yuan, J Li, D Jiang, J Zhang, H Li… - Gut, 2019 - gut.bmj.com
Objective to investigate whether diets differing in fat content alter the gut microbiota and
faecal metabolomic profiles, and to determine their relationship with cardiometabolic risk …

Microbiome and metabolome features of the cardiometabolic disease spectrum

S Fromentin, SK Forslund, K Chechi… - Nature medicine, 2022 - nature.com
Previous microbiome and metabolome analyses exploring non-communicable diseases
have paid scant attention to major confounders of study outcomes, such as common, pre …

Neuroactive compounds in foods: Occurrence, mechanism and potential health effects

C Yılmaz, V Gökmen - Food Research International, 2020 - Elsevier
Neuroactive compounds are synthesized by certain plants and microorganisms by
undertaking different tasks, especially as a stress response. Most common neuroactive …

gutSMASH predicts specialized primary metabolic pathways from the human gut microbiota

V Pascal Andreu, HE Augustijn, L Chen… - Nature …, 2023 - nature.com
The gut microbiota produce hundreds of small molecules, many of which modulate host
physiology. Although efforts have been made to identify biosynthetic genes for secondary …

[HTML][HTML] Gut microbiome fermentation determines the efficacy of exercise for diabetes prevention

Y Liu, Y Wang, Y Ni, CKY Cheung, KSL Lam, Y Wang… - Cell Metabolism, 2020 - cell.com
Exercise is an effective strategy for diabetes management but is limited by the phenomenon
of exercise resistance (ie, the lack of or the adverse response to exercise on metabolic …

Differences in fecal microbial metabolites and microbiota of children with autism spectrum disorders

DW Kang, ZE Ilhan, NG Isern, DW Hoyt, DP Howsmon… - Anaerobe, 2018 - Elsevier
Evidence supporting that gut problems are linked to ASD symptoms has been accumulating
both in humans and animal models of ASD. Gut microbes and their metabolites may be …

Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut

HM Roager, L Hansen, MI Bahl, HL Frandsen… - Nature …, 2016 - nature.com
Little is known about how colonic transit time relates to human colonic metabolism and its
importance for host health, although a firm stool consistency, a proxy for a long colonic …

Identification of phenol- and p-cresol-producing intestinal bacteria by using media supplemented with tyrosine and its metabolites

Y Saito, T Sato, K Nomoto, H Tsuji - FEMS microbiology ecology, 2018 - academic.oup.com
To identify intestinal bacteria that produce phenols (phenol and p-cresol), we screened 153
strains within 152 species in 44 genera by culture-based assay using broth media …